Overview
This volume on glutathione transferases and gamma-glutamyl transpeptidases serves to bring together current methods and concepts in an interesting, important and rapidly developing field of cell and systems biology. It focuses on particular aspects of the so-called Phase II of drug detoxication, which has important ramifications for endogenous metabolism and nutrition. This volume of Methods in Enzymology presents current knowledge and in this field of research. Together with the volumes on Quinones and Quinone Enzymes (volumes 378 and 382), and on Phase II Conjugation Enzymes and Transport Systems (volume 400), the state of knowledge on proteomics and metabolomics of many pathways of (waste) product elimination, enzyme protein induction and gene regulation and feedback control is provided. We trust that this volume will help stimulate future investigations and speed the advance of knowledge in systems biology.
Full Product Details
Author: Helmut Sies (Heinrich-Heine-University Düsseldorf, Germany) ,
Lester Packer (Department of Molecular Pharmacology and Toxicology, School of Pharmaceutical Sciences, University of Southern California, USA) ,
Helmut Sies (Heinrich-Heine-University Dusseldorf, Germany) ,
Helmut Sies (Heinrich-Heine-University Dusseldorf, Germany)
Publisher: Elsevier Science Publishing Co Inc
Imprint: Academic Press Inc
Volume: v. 401
Dimensions:
Width: 15.20cm
, Height: 2.70cm
, Length: 22.90cm
Weight: 0.860kg
ISBN: 9780121828066
ISBN 10: 0121828069
Pages: 928
Publication Date: 12 December 2005
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Hardback
Publisher's Status: Unknown
Availability: In Print
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.
Author Information
Helmut Sies is an Honorary Member of the American Society for Biochemistry and Molecular Biology. He received an Honorary Ph.D. from the University of Buenos Aires, Argentina in 1996. Dr. Sies is a member of the Northrhine-Westphalian Academy of Sciences, Germany, and a Corresponding Member of both the Academy of Sciences of Heidelberg, Germany, and the Academy of Medicine, Buenos Aires, Argentina. He has received many awards and prizes, including the FEBS Anniversary Prize awarded by the Federation of European Biochemical Societies, 1978; the Distinguished Foreign Scholar award, MASUA, 1985; the Silver Medal, Karolinska Institute, Stockholm, 1986; the Ernst Jung Preis fur Medizin, 1988; the Claudius-Galenus-Preis, 1990; and the ISFE-Preis, 1994. Dr. Sies sereves on the editorial board and advisory committee for twelve journals, has edited numerous books, and has published more than 400 original articles and chapters. He received his M.D. at the University of Munich in 1967 and currently serves as Full Professor and Chairman of the Department of Physiological Chemistry at the University of Dusseldorf.
