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OverviewGastroesophageal Reflux Disease (GERD) is one of the most common maladies of mankind. Approximately 40 per cent of the adult population of the USA suffers from significant heartburn and the numerous antacids advertised incessantly on national television represents a $8 billion per year drug market. The ability to control acid secretion with the increasingly effective acid-suppressive agents such as the H2 blockers (pepcid, zantac) and proton pump inhibitors (nexium, prevacid) has given physicians an excellent method of treating the symptoms of acid reflux. Unfortunately, this has not eradicated reflux disease. It has just changed its nature. While heartburn, ulceration and strictures have become rare, reflux-induced adenocarcinoma of the esophagus is becoming increasingly common. Adenocarcinoma of the esophagus and gastric cardia is now the most rapidly increasing cancer type in the Western world. The increasing incidence of esophageal adenocarcinoma has created an enormous interest and stimulus for research in this area.; Gerd is important because it will allow the presentation of the entire pathogenesis in one place without little bits of the concept being scattered around and difficult to locate in the mass of literature that exists. While providing a new concept about how gastroesophageal reflux causes cellular changes in the esophagus, this book will also provide a complete solution to a problem that has confused physicians for over a century. Clinical and pathological information about reflux disease and its treatment are included in this text that is meant to be used as a comprehensive reference. Full Product DetailsAuthor: Parakrama T Chandrasoma , Tom R Demeester , Para ChandrasomaPublisher: Elsevier Science & Technology Imprint: Elsevier Science & Technology ISBN: 9786610636648ISBN 10: 6610636648 Pages: 464 Publication Date: 18 September 2006 Audience: General/trade , General Format: Electronic book text Publisher's Status: Active Availability: Out of stock The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |