Overview

The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume stands as the first ever thematic volume in the series, focusing on the topic of genomics in cancer drug development. The chapters included in this book represent the cutting-edge information in the field and span such topics as Mass Spectrometry: Uncovering the Cancer Proteome for Diagnostics; Biomarker Discovery in Epithelial Ovarian Cancer by Genomic Approaches; The Application of siRNA Technology to Cancer Biology Discovery; Ribozyme Technology for Cancer Gene Target Identification and Validation; Cancer Cell-Based Genomic and Small Molecule Screens; Tumour Antigens as Surrogate Markers and Targets for Therapy and Vaccines; Practices and Pitfalls of Mouse Cancer Models in Drug Discovery; Biomarker Assay Translation from Discovery to Clinical Studies in Cancer Drug Development - Quantification of Emerging Protein Biomarkers; Molecular Optical Imaging of Therapeutic Targets of Cancer; Cancer Drug Approval in the United States, Europe and Japan.

Full Product Details

Author:   George Klein ,  George F. Vande Woude ,  Garrett Hampton ,  Karol Sikora
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Edition:   96th edition
Volume:   v. 96
Weight:   0.940kg
ISBN:  

9780120066964

ISBN 10:   0120066963
Pages:   432
Publication Date:   01 December 2006
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Available To Order  
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Table of Contents

Mass Spectrometry: Uncovering the Cancer Proteome for Diagnostics.Biomarker Discovery in Epithelial Ovarian Cancer by Genomic Approaches.The Application of siRNA Technology to Cancer Biology Discovery.Ribozyme Technology for Cancer Gene Target Identification and Validation.Cancer Cell-Based Genomic and Small Molecule Screens.Tumour Antigens as Surrogate Markers and Targets for Therapy and Vaccines.Practices and Pitfalls of Mouse Cancer Models in Drug Discovery.Biomarker Assay Translation from Discovery to Clinical Studies in Cancer Drug Development - Quantification of Emerging Protein Biomarkers.Molecular Optical Imaging of Therapeutic Targets of Cancer.Cancer Drug Approval in the United States, Europe and Japan.

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