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OverviewFor more than a century, knowledge about the role of genes has been gradually reshaping perceptions of our health and of ourselves. From Mendel's work with plants and Watson and Crick's model of DNA's double-helix structure to the recent decoding of the human genome, the tremendous advances in our ability to analyze and interpret gene sequences are revolutionizing many aspects of medicine. Genomic Medicine collects and updates an acclaimed series of articles published in the pages of the New England Journal of Medicine since November 2002 that together provide an authoritative and comprehensive overview of the latest developments in the field of medical genetics and an exploration of where these advances might take medicine over the next decade. Beginning with a fundamental primer and a useful glossary of terms, the book offers the latest information on the use of genetics to screen, diagnose, and treat a wide variety of diseases, including breast and ovarian cancer and cardiovascular, Alzheimer, and Parkinson disease. Also included are discussions of population screening, pharmacogenetics, and the ethical, legal, and social dimensions of genomic medicine. Edited by leaders in the field, written by experts from around the globe, and brimming with full-color illustrations, Genomic Medicine is an indispensable guide to the full potential of the DNA-based transformation of medicine. Full Product DetailsAuthor: Alan E. Guttmacher, MD (Deputy Director, National Institutes of Health) , Francis S. Collins, MD PhD (Director, National Institutes of Health) , Jeffrey M. Drazen, MD (Editor-in-Chief, New England Journal of Medicine) , Elias Zerhouni, MDPublisher: Johns Hopkins University Press Imprint: Johns Hopkins University Press Dimensions: Width: 17.80cm , Height: 1.20cm , Length: 25.40cm Weight: 0.567kg ISBN: 9780801879791ISBN 10: 0801879795 Pages: 208 Publication Date: 20 April 2004 Recommended Age: From 18 Audience: General/trade , Professional and scholarly , College/higher education , General , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Out of stock The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available. Table of ContentsForeword Preface List of Contributors Glossary Chapter 1. Getting Ready for Gene-Based Medicine Chapter 2. Genomic Medicine - A Primer Chapter 3. Genetic Testing Chapter 4. Population Screening in the Age of Genomic Medicine Chapter 5. Inheritance and Drug Response Chapter 6. Pharmacogenomics - Drug Disposition, Drug Targets, and Side Effects Chapter 7. Pharmacogenetics in the Laboratory and the Clinic Chapter 8. Hereditary Colorectal Cancer Chapter 9. Alzheimer's Disease and Parkinson's Disease Chapter 10. Molecular Diagnosis of the Hematologic Cancers Chapter 11. Breast and Ovarian Cancer Chapter 12. Cardiovascular Disease Chapter 13. Ethical, Legal, and Social Implications of Genomic Medicine Chapter 14. Genomics as a Probe for Disease Biology Chapter 15. Welcome to the Genomic Era IndexReviewsAn indispensable guide to the full potential of the DNA-based transformation of medicine. Human Reproduction and Genetic Ethics The editors have assembled a fine set of short, readable and highly authoritative articles by eminent authors. The book is beautifully produced and will give an accessible entry into genetic medicine to its target audience of non-specialist clinicians. Readers of this journal will need no persuading of the fascination and ever growing importance of genetic medicine and these themes are well communicated. -- Andrew P. Read Human Genetics 2004 Fifteen years ago, many questioned the wisdom of sequencing the human genome. There were concerns not only about the technical feasibility of such an effort, but also that its scientific worth would prove too modest to warrant the investment of human and financial capital that the project would require. This collection of essays stands as eloquent testimony to those who overcame such doubts to create, nurture, and finish the sequencing of the human genome in April 2003, a date that will forever stand out in human history. - from the foreword by Dr. Elias Zerhouni Author InformationFrancis S. Collins, M.D., Ph.D., is director of the National Human Genome Research Institute (NHGRI) at the National Institutes of Health. He shepherded the Human Genome Project to completion in 2003. Alan E. Guttmacher, M.D., is deputy director of the NHGRI and director of its Office of Policy, Communication, and Education. Jeffrey M. Drazen, M.D., is Editor-in-Chief of the New England Journal of Medicine. Tab Content 6Author Website:Countries AvailableAll regions |
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