Overview

The field of Molecular Diagnostics is rapidly evolving and molecular characterization of neoplasms is becoming an increasingly important part of the pathologic work up and diagnosis of many tumor types. This work provides a high-yield reference book that compiles critical information related to molecular biomarkers for various solid tumor and hematologic malignancy subtypes. It is succinct yet comprehensive enough to be suitable for fellows in training and medical professionals with an interest in molecular pathology and biomarkers. The book covers many aspects of molecular diagnostics, from techniques to applications and comprehensive summaries of the current molecular biomarkers of critical importance in solid and liquid tumors. Attention is also specifi cally devoted to bioinformatics and next generation sequencing, as well as pre-analytical issues that must be considered for accurate interpretation of molecular results in the context of overall patient care. This text focuses on clinical utility and validity and serves as an “owner’s manual” in Genomic Diagnostics for the practicing pathologist, pathology fellows and residents and other health care providers. Physicians will find this book invaluable as a quick reference for current molecular testing modalities and guidelines, tumor board preparation, deciding which test to order and interpreting genomic laboratory results. In addition, it is an accessible for trainees as a board review preparation reference.

Full Product Details

Author:   Laura J. Tafe ,  Maria E. Arcila
Publisher:   Springer Nature Switzerland AG
Imprint:   Springer Nature Switzerland AG
Edition:   1st ed. 2020
Weight:   0.807kg
ISBN:  

9783030229214

ISBN 10:   3030229211
Pages:   325
Publication Date:   16 October 2019
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

PREFACE Laura J. Tafe, MD and Maria E. Arcila, MD   PART I: GENERAL CONCEPTS Chapter 1:  Pre-Analytics, Current Testing Technologies, and Limitations of Testing Alejandro Luiña Contreras, MD; Jose Jasper C. Andal, MD; Raymundo Lo, MD; Daphne Chua Ang, MD Chapter 2: Next Generation Sequencing Alanna J. Church, M.Sc., M.D. Chapter 3: Cell Free DNA Testing Brennan Decker, MD, PhD and Lynette M. Sholl, MD Chapter 4: Role of Bioinformatics in Molecular Medicine Chad Vanderbilt, M.D., Sumit Middha, Ph.D. Chapter 5: Interpreting Genomic Reports Alejandro Luiña Contreras, M.D.   PART II: APPLICATIONS IN SOLID TUMORS Chapter 6: Lung Carcinoma Maria E Arcila, Jason C Chang, Laura J Tafe Chapter 7: GI including GIST Efsevia Vakiani, MD, PhD Chapter 8: Breast Dara S. Ross, MD   Chapter 9: Genitourinary Tumors Marie-Lisa Eich and George J. Netto Chapter 10: Gynecologic Malignancies Jessica L. Dillon, MD and Laura J. Tafe, MD Chapter 11: Sarcomas Konstantinos Linos MD, FCAP, FASDP Chapter 12: Salivary Gland Carcinomas Snjezana Dogan, MD Chapter 13: Sinonasal Carcinomas Snjezana Dogan, MD   PART III: APPLICATIONS IN HEMATOPATHOLOGY Chapter 14: Acute Myeloid Neoplasms Eric Y. Loo, MD Chapter 15: Chronic Myeloid Neoplasms Maria E. Arcila and Caleb Ho Chapter 16: Lymphomas Vignesh Shanmugam, MD and Annette S. Kim, MD, PhD

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Author Information

Laura J. Tafe, MDAssociate Professor of Pathology and Laboratory MedicineDepartment of Pathology and Laboratory MedicineDartmouth-Hitchcock Medical CenterOne Medical Center DriveLebanon, NH 03756603-650-7211 Maria E. Arcila, MDAssociate attending Department of Pathology – Hematopathology and Molecular Diagnostics Services Memorial Sloan Kettering Cancer Center 1275 York AveNew York, NY 10065212 6397879

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