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OverviewThis book discusses the molecular, biological, pathological, and clinical aspects of melanoma, with special emphasis in the new concepts of melanoma genetics. A multidisciplinary group of experts in Genetics, Dermatology, Pathology, and Melanoma Medical Oncology contribute state-of-the-art knowledge in melanoma research and clinical management, not only exposing the current status of knowledge of the topics but also providing their personal experiences and ideas about the future and potential practical application of the genetic aspects of melanoma. During the last few years we have witnessed an impressive amount of discoveries in the field of melanoma genetics which have changed our approach in understanding the pathogenesis and treatment of this lethal disease. Genetics of Melanoma is a practical approach to melanoma genetic mechanisms and their application in the diagnosis and treatment of this malignancy. It is an essential source of updated information and a powerful tool for clinicians, pathologists, and basic scientists who wish to understand, apply, and investigate the multiple new aspects of melanoma genetics. Full Product DetailsAuthor: Carlos A. Torres-Cabala , Jonathan L. CurryPublisher: Springer-Verlag New York Inc. Imprint: Springer-Verlag New York Inc. Edition: 1st ed. 2016 Dimensions: Width: 15.50cm , Height: 1.90cm , Length: 23.50cm Weight: 5.856kg ISBN: 9781493935529ISBN 10: 1493935526 Pages: 288 Publication Date: 12 May 2016 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Manufactured on demand ![]() We will order this item for you from a manufactured on demand supplier. Table of ContentsBiology of Melanoma.- The Role of the Immune System and Immunoregulatory Mechanisms Relevant to Melanoma.- Epidemiology and Clinical Characteristics of Melanoma.- Pathology of Melanoma.- Inherited Gene Mutations in Melanoma.- The MAPK Pathway in Melanoma.- The PI3K-AKT Pathway in Melanoma.- Biomarker Analysis for BRAF, NRAS, KIT, and BAP-1 Expression in Melanoma.- Molecular Platforms in Melanoma Mutation Analysis.- Immunotherapy in Melanoma.- Molecular Targeted Therapy in Melanoma.- Dermatologic Toxicities to Melanoma Targeted Therapy.ReviewsAuthor InformationCarlos A. Torres-Cabala, MD, Associate Professor of Pathology and Dermatology, Chief of Dermatopathology Section, The University of Texas MD Anderson Cancer Center, Houston, TXJonathan L. Curry, MD, Associate Professor of Pathology and Dermatology, The University of Texas MD Anderson Cancer Center, Houston, TX Tab Content 6Author Website:Countries AvailableAll regions |