Overview

Cardiology is entering a new era-an era in which the stethoscope, echocardiogram, angiogram, and ECG are no longer the only tools that guide expert heart care. Today, genes, variants, inherited patterns, and molecular pathways are becoming equally important in understanding why cardiovascular disease begins, how it progresses, and how it can be prevented, diagnosed, and treated with greater precision. Genetics and Cardiology: A Guide to Expert Cardiac Care is written to help bridge that crucial gap between classical cardiology and the rapidly expanding world of cardiovascular genetics. For decades, heart disease was approached mainly through symptoms, risk factors, imaging, and intervention. While these remain essential, modern practice increasingly reveals that behind many cardiac conditions lies a genetic framework that shapes disease expression, patient risk, family screening, and long-term outcomes. Sudden cardiac death in the young, unexplained cardiomyopathies, inherited arrhythmias, familial hypercholesterolemia, connective tissue disorders affecting the aorta, congenital heart disease, and even varying responses to drugs may all carry a genetic signature. Recognizing that signature can transform patient care. This book is designed for clinicians, cardiologists, physicians in training, researchers, students, and all healthcare professionals who wish to understand how genetics is reshaping cardiovascular medicine. It aims to present complex concepts in a practical, clinically relevant, and accessible manner. Rather than treating genetics as a distant laboratory science, this book places it where it belongs-in the clinic, in the cath lab, in the intensive care unit, in preventive cardiology, and in family-based risk assessment. Within these pages, readers will explore the foundations of human genetics as applied to cardiovascular disease, the principles of inheritance, the role of gene mutations and variants, and the interpretation of genetic testing in real-world practice. The book also addresses the expanding role of genomics in cardiomyopathies, arrhythmia syndromes, lipid disorders, aortopathies, congenital syndromes, and precision therapeutics. Equally important, it discusses how to counsel families, identify red flags in inherited cardiac disease, and integrate genetic insight into decision-making with confidence and responsibility. The goal of this book is not merely to inform, but to empower. Inherited cardiac disorders are often underrecognized until tragedy occurs. A patient with syncope, a family history of premature sudden death, an athlete with unexplained left ventricular hypertrophy, or a child from a family with severe hypercholesterolemia may all represent opportunities for life-saving diagnosis. Genetics gives the clinician a wider lens-a way to see beyond the individual patient and protect entire families through early recognition and targeted intervention. At the same time, genetics must be approached with clinical wisdom. A gene report alone does not treat a patient. The true art of expert cardiac care lies in integrating history, examination, imaging, electrophysiology, biomarkers, intervention, and genetic data into a meaningful and compassionate plan. This book has been created with that philosophy in mind: science guided by bedside judgment, and innovation directed toward better human outcomes. Genetics and Cardiology: A Guide to Expert Cardiac Care is therefore more than a scientific overview. It is a practical clinical companion for the present and the future of cardiovascular medicine. As precision medicine continues to evolve, the cardiologist who understands genetics will be better equipped to diagnose earlier, stratify risk more accurately, personalize treatment more effectively, and protect families more completely.

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