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OverviewInfectious diseases are commonly regarded as a distinct category, with different causes and patterns than chronic or genetic disease. But in fact there are many varieties of genetic susceptibility to infection, the subject of this book, which will be divided into three sections: 1) concepts and methods, 2) genes and pathophysiologic mechanisms, and 3) infectious agents and diseases. No currently plubished text on either genetics or infectious diseases focuses on the genetic aspects of the special relationship between host and pathogen in the way envisioned for Section 1. No other work on the selected genes regulating immunity deals as systematically with the sequence variation/function relationships most pertinent to infection as planned for Section 2. And no other book gives as meaningful a picture of how these genes operate in infectious disease as Section 3 will. Full Product DetailsAuthor: Richard A. Kaslow (Professor of Epidemiology and International Health, Medicine, and Microbiology, University of Alabama) , Janet M. McNicholl (Centers for Disease Control and Prevention) , Adrian V. S. Hill (Wellcome Trust Centre for Human Genetics, University of Oxford)Publisher: Oxford University Press Inc Imprint: Oxford University Press Inc Dimensions: Width: 18.70cm , Height: 2.50cm , Length: 26.10cm Weight: 0.993kg ISBN: 9780195174908ISBN 10: 0195174909 Pages: 464 Publication Date: 11 December 2007 Audience: College/higher education , Professional and scholarly , Postgraduate, Research & Scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Manufactured on demand ![]() We will order this item for you from a manufactured on demand supplier. Table of ContentsSECTION I: METHODS AND TOOLS ; 1. Genetic Epidemiology of Infectious Disease ; 2. Laboratory Analysis of Genetic Variation ; 3. Mouse Models for Geentic Susceptibility to Infection in Humans ; SECTION II: IMMUNE RESPONSE GENES AND INFECTION ; 4. MHC Class I and Related Genes ; 5. MHC Class II and Related Genes ; 6. MHC Class I Polypeptide-Related Sequence A and B (MICA and MICB) Genes ; 7. Killer Immunoglobulin-Like Receptor and Related Genes ; 8. Red Blood Cell Genes ; 9. Immunoglobulin (Fc) Receptor and Related Genes ; 10. Mannose-Binding Lectin Genes ; 11. Complement Genes ; 12. Toll-Like Receptor Genes ; 13. Metal Transport Genes ; 14. Tumor Necrosis Factor and Related Genes ; 15. Cytokine Genes I (IL10, IL6, IL4, and the IL1 Family) ; 16. Cytokine Genes II (IFNG, IL12 and Their Receptor Genes) ; 17. Chemokine Receptor and Ligand Genes ; SECTION III: GENETIC DETERMINANTS OF INFECTIOUS DISEASES AND RESPONSE TO VACCINES ; 18. Immune Deficiency Disorders ; 19. Human Immunodeficiency Virus, Type 1 (HIV-1) and Acquired Immunodeficiency Syndrome ; 20. Human T Lymphotropic Virus, Type 1 (HTLV-1)-Associated Diseases ; 21. Hepatitis B and Hepatitis C Infection ; 22. Tuberculosis, Leprosy and Other Mycobacterial Diseases ; 23. Diseases Due to Encapsulated Bacteria ; 24. Malaria ; 25. Leishmaniasis ; 26. Schistosomiasis ; 27. Genetics and Immune Response to VaccinesReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |