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Author:   John D. Potter ,  Noralane M. Lindor
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2009 ed.
Volume:   v. 1
Dimensions:   Width: 15.50cm , Height: 1.90cm , Length: 23.50cm
Weight:   1.390kg
ISBN:  

9780387095677

ISBN 10:   0387095675
Pages:   309
Publication Date:   08 December 2008
Audience:   General/trade ,  General
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Epidemiology and Models of Colorectal Cancer.- Colorectal Cancer: Epidemiology.- Mouse Models of Intestinal Cancer.- Pathways to Colorectal Cancer.- The Chromosomal-Instability Pathway and APC Gene Mutation in Colorectal Cancer.- DNA Methylation in Colorectal Cancer: Multiple Facets of Tumorigenesis.- Pathways and Pathology.- Germline Susceptibility – Mendelian and Other Syndromes.- Familial Adenomatous Polyposis.- DNA Mismatch Repair and Lynch Syndrome.- Additional Syndromes with Hereditary Predisposition to Colorectal Cancer.- Familial Colorectal Cancer Type X.- Families with Serrated Neoplasia of the Colon.- Peutz–Jeghers Syndrome.- Juvenile Polyposis.- BLM Mutation and Colorectal Cancer Susceptibility.- The Role of p53 in Colorectal Cancer.- Chromosomes 8q24 and 9p24: Associations with Colorectal Cancer.- Germline Susceptibility – Gene-Environment Interactions.- Genetic Variability in Folate-Mediated One-Carbon Metabolism and Risk of Colorectal Neoplasia.- Genetic Variability in NSAID Targets and NSAID-Metabolizing Enzymes and Colorectal Neoplasia.- The Role of Chemical Carcinogens and Their Biotransformation in Colorectal Cancer.- Calcium and Vitamin D.

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