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Author:   Thomas Blankenstein
Publisher:   Birkhauser Verlag AG
Imprint:   Birkhauser Verlag AG
Edition:   illustrated edition
Weight:   1.020kg
ISBN:  

9783764359720

ISBN 10:   3764359722
Pages:   392
Publication Date:   December 1998
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Out of stock  

Table of Contents

I. Gene Transfer Methods.- 1 Retroviral Vectors.- 2 Adenovirus Vectors for Gene Therapy.- 3 Receptor Mediated Gene Transfer.- 4 Liposomes in Gene Therapy.- 5 Recombinant Adeno-Associated Virus (r AAV) Vectors.- 6 Gene Transfection Using Particle Bombardment.- II. Gene Therapy of Single Gene Defects.- 1 Gene Therapy for Severe Combined Immunodeficiencies.- 2 Models of Lysosomal Storage Disorders Useful for the Study of Gene Therapy.- 3 Gene Therapy for Cystic Fibrosis.- 4 Gene Therapy of Familial Hypercholesterolemia.- III. Gene Marking.- 1 Gene Marking in Bone Marrow and Peripheral Blood Stem Cell Transplantation.- 2 Gene Marking of T Lymphocytes.- 3 MDR1 Gene Transfer to Hematopoietic Cells.- IV. Gene Therapy of Cancer.- 1 The c-myb Protooncogene: A Novel Target for Human Gene Therapy.- 2 Thymidine Kinases.- 3 Strategies for Enhancing Tumor Immunogenicity (or how to transform a tumor cell in a Frankenstenian APC).- 4 T Blankenstein Vaccines using Gene-Modified Tumor Cells.- 5 Autologous and Allogeneic Tumor Cell Vaccines.- 6 Identification of Tumor Antigens Defined by Cytolytic T Lymphocytes and Therapeutic Implications.- 7 Peptide Vaccination.- 8 Combination Effects of Gene Modified Tumor Cell Vaccines and Chemotherapy.

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