Overview

This book has been written in response to the many physicians and scien- tists working on the development of biological approaches to providing therapies for many orthopaedic disorders as well as to improving the healing of many tissues of the musculoskeletal system. The first goal of this book is to make the language compatible between the bench scientist and the clinician working in orthopaedic and sports medicine in order to cover specific areas of the orthopaedic discipline where the treatment can be improved and/or changed by the advancements in molecular medicine. Advancements in molecular biology, which encompass the study of the genetic basis of disease, have produced new diagnostic methods and drug therapies for genetic diseases and acquired disorders. The growth in the understanding of human genetics has also led to the initiation of many human gene therapy experiments. Although many approved therapeutic clinical trials using this new technology have been performed in the last ten years, the first clinical trial using this technology in the area of orthopaedics was performed at the University of Pittsburgh.

Full Product Details

Author:   Johnny Huard ,  Freddie H. Fu, M.D. ,  Huard J. (Children's Hospital of Pittsburgh and the University of Pittsburgh, USA)
Publisher:   Birkhauser Boston Inc
Imprint:   Birkhauser Boston Inc
Edition:   2000 ed.
Dimensions:   Width: 16.20cm , Height: 2.00cm , Length: 24.00cm
Weight:   0.560kg
ISBN:  

9780817640712

ISBN 10:   0817640711
Pages:   286
Publication Date:   11 August 2000
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Out of stock  

Table of Contents

1. Gene Therapy in Orthopaedics. C. Lattermann, H. Fu 2. The Use of Different Viral Vectors and Strategies for Gene Transfer to the Musculoskeletal System. J. Huard 3. Regional Gene Therapy for Hard Tissues. J.R. Lieberman 4. Potential Applications of Gene Therapy to the Treatment of Spinal Disorders. K. Nishida, J.D. Kang, S.D. Boden, L.G. Gilbertson, J.K. Suh, P.D. Robbins, C.H. Evans 5. The Development of Approaches Based on Gene Therapy to Improve Muscle Healing Following Injury. J. Menetrey, C. Kasemkijwattana, C.S. Day, P. Bosch, M.S. Moreland, F.H. Fu, J. Huard 6. Non-Viral Gene Therapy: Application in the repair of osteochondral articular defects. R.S. Goomer, D.A. Amiel 7. The Potential of Gene Therapy for Osteogenesis Imperfecta. C. Niyibizi, P.N. Smith, J. Greenberg 8. The Role of Nitric Oxide as a Candidate Molecule for Gene Therapy in Sports Injuries. S.A. Rodeo, K. Izawa 9. Stem Cells and Tissue Engineering. H.E. Young 10. Tissue Engineering of Ligament Healing. S. Woo, N. Watanabe, K.A. Hildebrand 11. Muscle Based Tissue Engineering for Orthopaedic Applications. D.S. Musgrave, C.S. Day, P. Bosch, J. Menetrey, C. Kasemkijwattana, M.S. Moreland, F.H. Fu, J. Huard 12. Application of Tissue Engineering to Cartilage Repair. J.K. Suh, F.H. Fu 13. Immune Reaction Following Cell and Gene Therapy. J.P. Tremblay 14. Vectors for Gene Transfer to Joints. P.D. Robbins, S.C. Ghivizzani, J.C. Glorioso, C.H. Evans 15. The Use of Adeno-Associated Virus for the Musculoskeletal System. X. Xiao, R. Pruchnic, J. Li, J. Huard Index

Reviews

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions