Overview
Clinical and preclinical exploration of gene and cellular immunotherapy have seen rapid growth and interest with the development and approval of five Chimeric Antigen Receptor T-cell (CAR-T) products for lymphoma and myeloma and one Bispecific T-Cell Engager (BiTE) for acute lymphoblastic leukemia (ALL). These advances have dramatically improved the management of patients with relapsed refractory lymphoma, myeloma and leukemia. Gene and Cellular Immunotherapy for Cancer offers readers a comprehensive review of current cellular and gene-based immunotherapies. Divided into eighteen cohesive chapters, this book provides an in-depth and detailed look into cellular-based immunotherapies including CAR-T, TCR-T, TIL, Viral CTLs, NK cells in addition to T/NK cell engagers, focusing on their historical perspectives, biology, development and manufacturing, toxicities and more. Edited by two leading experts on gene and cellular immunotherapy, the book will feature chapters written by a diverse collection of recognized and up-and-coming experts and researchers in the field, providing oncologists, immunologists, researchers and clinical and basic science trainees with a bench to bedside view of the latest developments in the field.
Full Product Details
Author: Armin Ghobadi ,
John F. DiPersio
Publisher: Springer Nature Switzerland AG
Imprint: Springer Nature Switzerland AG
Edition: 1st ed. 2022
Weight: 0.593kg
ISBN: 9783030878511
ISBN 10: 3030878511
Pages: 378
Publication Date: 21 December 2022
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Paperback
Publisher's Status: Active
Availability: Manufactured on demand
We will order this item for you from a manufactured on demand supplier.
Author Information
Armin Ghobadi is an Associate Professor in the Division of Oncology and clinical director of the Center for Gene and Cellular Immunotherapy (CGCI) at Washington University School of Medicine in St. Louis, and a member of the Alvin J. Siteman Cancer Center. He earned his Medical Diploma at Iran University of Medical Sciences and Health Services School of Medicine in Tehran. Ghobadi’s post graduate training has been at the University of Texas Southwestern Medical School in Dallas, TX, the MD Anderson Cancer Center in Houston, TX and Washington University School of Medicine in St. Louis. Currently his research focuses on cellular therapy for hematologic malignancies, hematopoietic stem cell transplantation, and genome sequencing John F. DiPersio is the Deputy Director of Alvin J. Siteman Cancer Center, Samuel J. Goldman Endowed Professor of Oncology, Chief of the Division of Oncology, and director of the Center for Gene and Cellular Immunotherapy (CGCI) at Washington University School of Medicine inSt. Louis. DiPersio earned a BA in Biology at Williams College in Williamstown, MA and a Ph.D./MD in Microbiology at the University of Rochester, Rochester, NY. Currently, his research focuses on hematopoietic stem cell mobilization, murine models of graft-versus host disease and graft-versus leukemia, leukemia genomics and targeted cellular therapies for the treatment of leukemias.
