Overview

Gastrulation is a fundamental process of early embryonic development. It involves virtually every aspect of cell and developmental biology and results in the formation of fundamental structural elements around which a developing animal's body plan is organized. As such it is not only an important process, but also one that is complicated and not easily dissected into its component parts. To understand the mechanisms of gastrulation one must acknowledge that gastrulation is fundamentally a biomechanical process (that is, a problem of cells generating forces in a three dimensional array, patterned in space and time such that appropriate tissue movements are executed). Three intertwined questions emerge: what cell activities generate forces, how are these cell activities patterned in space and time, and how are the resulting forces harnessed in three dimensional domains? To address these issues it is important to define and characterize regional cell behaviors and to learn how they are patterned in the egg and/ or by subsequent cell and tissue interactions. At the biochemical level, what are the cellular and extracellular molecules that control cell behavior? Finally, how are specific patterns of cellular activity integrated to produce tissue behavior? The task of answering the above questions, an immense task in itself, is compounded by the fact that the morphogenetic movements of gastrulation and their underlying mechanisms vary between different organisms.

Full Product Details

Author:   Ray Keller ,  Wallis H. Clark Jr. ,  Frederick Griffin
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   Softcover reprint of the original 1st ed. 1991
Dimensions:   Width: 15.50cm , Height: 1.80cm , Length: 23.50cm
Weight:   0.534kg
ISBN:  

9781468460292

ISBN 10:   1468460293
Pages:   332
Publication Date:   03 March 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Cell Movements in the Epiblast During Gastrulation and Neurulation in Avian Embryos.- Mesoderm Formation in the Chick Embryo, Revisited.- Culture of Embryonic Cells for Analysis of Amphibian and Mammalian Early Embryogenesis.- Organizing the Xenopus Organizer.- The Arrangement of Early Inductive Signals in Relation to Gastrulation; Results from Frog and Chick.- Cell Motility, Control and Function of Convergence and Extension During Gastrulation in Xenopus.- In vivo Analysis of Convergent Cell Movements in the Germ Ring of Fundulus.- Dynamical Models for Cell Rearrangement During Morphogenesis.- Mesoderm Cell Migration in the Xenopus Gastrula.- Amphibian Gastrulation: The Molecular Bases of Mesodermal Cell Migration in Urodele Embryos.- The Expression of Fibronectins and Integrins During Mesodermal Induction and Gastrulation in Xenopus.- Mechanics and Genetics of Cell Shape Changes During Drosophila Ventral Furrow Formation.- Convergence and Extension During Germband Elongation in Drosophila Embryos.- Ultraviolet-Sensitive Determinants of Gastrulation and Axis Development in the Ascidian Embryo.- Rapid Evolution of Early Development: Reorganization of Early Morphogenetic Processes in a Direct-Developing Sea Urchin.- Sea Urchin Micromeres, Mesenchyme, and Morphogenesis.- Primary Mesenchyme Cell Migration in the Sea Urchin Embryo.- Cell-Extracellular Matrix Interactions During Primary Mesenchyme Formation in the Sea Urchin Embryo.- The Role of Cell Adhesion During Gastrulation in the Sea Urchin.

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