Overview

Disorders of gastrointestinal transit are among the major causes of ill-health and, today, provide one of the most common reasons for specialist referral. Fortunately, however, recent developments in measuring techniques - including some that are non-invasive - have made the quantification of gastrointestinal motility feasible, and a number of new drugs are now available that specifically influence the enteric nervous system, leading to great advances in the management of gastointestinal disorders. This volume presents up-to-date information about gastrointestinal motility. Focusing particularly on the physiological and pharmacological aspects of intestinal transit, the contributors shed much light on this complex subject.

Full Product Details

Author:   Michael A. Kamm ,  John E.Lennard- Jones ,  John E. Lennard-Jones
Publisher:   Wrightson Biomedical Publishing Ltd
Imprint:   Wrightson Biomedical Publishing Ltd
Weight:   0.635kg
ISBN:  

9781871816112

ISBN 10:   1871816114
Pages:   272
Publication Date:   01 May 1991
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
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Table of Contents

Part 1 Physiological control of gastrointestinal transit: cerebral and spinal control of gastrointestinal motor functions, Lionel Bueno and Jean Fioramonti; extrinsic autonomic control of human gastrointestinal transit, David G. Thompson; enteric nervous system - neural connections, neurotransmitters and the function of 5-hydroxytryptamine, Michael D. Gershon; circulating hormonal control, John Calam and Raymond Playford. Part 2 Motor physiology: an overview of the physiology of gastric motility, Juan-R. Malagelada; the small intestine and the ileal brake, N.W. Read and N.J. Brown; motor physiology of the human colon, Jan D. Huizinga. Part 3 Measurement of transit: measurement of transit - oesophagus and stomach, L.M.A. Akkermans and D.R. Fone; measurement of small-bowel transit in humans, N.W. Read; measurement of colonic transit, Sidney F. Phillips. Part 4 Clinical disorders of transit and their treatment: clinical disorders of oesophageal transit and gastric emptying, R.C. Heading and J.S. De Caestecker; constipation, Michael A. Kamm; diarrhoea, R.C. Spiller; chronic intestinal pseudo-obstruction, P.J. Milla. Part 5 Pharmocology of substances which influence transit: pharmacotherapy of gastrointestinal transit, J. Schuurkes; prokinetic substituted benzamides - in vitro studies of their mechanism of action, J. Schuurkes; mechanisms of action of laxatives, Jean Fioramonti and Lionel Bueno; effects of long-term treatment with Senna on neuromuscular transmission in the large intestine of the rat, Charles H.V. Hoyle; fibre and bulk preparations, K.W. Heaton; antidiarrhoeal drugs, D. Burleigh; drugs acting on potassium or calcium channels - effects on gastrointestinal motility, Jan D. Huizinga. Part 6 The clinical problem: correlation of symptoms, measurements and treatment, David Wingate.

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