Overview

Few fields have advanced faster over the past quinquennium than separation and estimation of steroids by the technique of gas phase chromatography. A detailed and complete review of this topic would therefore be beyond the scope of the authors contributing to this monograph. It was, however, felt that a discussion of some of the highlights of this rapid advance might be of help for laboratories estimating steroids in biological samples. One of the difficulties in producing a monograph of this kind is that before it can appear in print it is likely that some of the methods it discusses will have been overtaken by better methods, so swiftly is progress now made. No editorial power has been exercised in trying to make a uni­ form account of technology in this field, and the idiosyncrasies of each individual author have been left intact. Through this approach we hope that what has been lost in scholarly appearance is regained in general appeal.

Full Product Details

Author:   Kristen B. Eik-Nes ,  Evan C. Horning
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 1968
Volume:   2
Dimensions:   Width: 15.20cm , Height: 2.10cm , Length: 22.90cm
Weight:   0.589kg
ISBN:  

9783642867958

ISBN 10:   3642867952
Pages:   384
Publication Date:   27 May 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1 Gas Phase Analytical Methods for the Study of Steroid Hormones and their Metabolites.- I. Historical.- II. Analytical Methods.- III. Instrumental Components.- IV. Derivatives.- V. Separation Methods.- VI. GLC Characterization of Steroids.- VII. Problems of Quantification.- VIII. Analytical Applications with High-sensitivity Selective Detection.- IX. Structural Analysis by Gas Chromatography-Mass Spectrometry.- X. Steroid Conjugates.- References.- 2 Gas Phase Chromatographic Methods for Estrogens in Biological Fluids.- I. Introduction.- II. General Considerations.- III. Use of Estrogen Derivatives.- IV. Quantification and Identification of Gas Chromatographic Peaks of Estrogens.- V. Methods for the Estimation of Estrogens in Biological Extracts.- VI. Conclusion.- References.- 3 Gas Phase Chromatography of Progesterone and Related Steroids.- I. Introduction.- II. Progesterone and Reduced Metabolites: Progesterone, 20?- and 20?-Hydroxypregn-4-en-3-one, 3? and 3?-Hydroxypregn-4-en-3-one, and Pregn-4-ene-3,20-Diols.- III. Pregnanolones.- IV. Pregnanediols.- V. 17?-Hydrogyprogesterone and Reduced Metabolites.- VI. Pregnanetriol in Human Urine.- VII. 6-Oxygenated Progesterone and Reduced Metabolites.- VIII. 11-Oxygenated Progesterone and Reduced Metabolites.- IX. 16-Oxygenated Progesterone and Reduced Metabolites.- X. 17?-Pregnanes.- XI. Other Pregnanes.- References.- 4 Gas Phase Chromatography of Androgens in Biological Samples.- I. Introduction.- II. Androgens in Blood Plasma.- III. Androgens in Urine.- References.- 5 Gas Phase Chromatography of Corticosteroids in Biological Samples.- I. Introduction.- II. Cortisol, Prednisolone and Some of Their Metabolites.- III. Corticosterone and its Metabolites.- IV. Aldosterone.- V. Conclusion.- References.- Trivial andSystematic Names of Steroids.- Author Index.- Compound Index.- Steroid Technique Index.- Steroid Assay Index.

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