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Author:   Jaime M. Monti ,  Seithikurippu Ratnas Pandi-Perumal ,  Hanns Möhler
Publisher:   Birkhauser Verlag AG
Imprint:   Birkhauser Verlag AG
Dimensions:   Width: 15.50cm , Height: 3.00cm , Length: 23.50cm
Weight:   1.028kg
ISBN:  

9783034602259

ISBN 10:   3034602251
Pages:   486
Publication Date:   30 September 2010
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Basic Physiology and Pharmacology.- Physiology and Pharmacology of the GABA System: Focus on GABA Receptors.- Development of Subtype-Selective GABAA Receptor Compounds for the Treatment of Anxiety, Sleep Disorders and Epilepsy.- Distribution of GABAA Receptor Subunits in the Human Brain.- Pharmacokinetic Determinants of the Clinical Effects of Benzodiazepine Agonist Hypnotics.- Sleep Science and Circuitry.- Sleep and Its Modulation by Substances That Affect GABAA Receptor Function.- Subcortical Neuromodulation of Feedforward and Feedback Inhibitory Microcircuits by the Reticular Activating System.- Function of GABAB and ?-Containing GABAA Receptors (GABAC Receptors) in the Regulation of Basic and Higher Integrated Sleep-Waking Processes.- Interactions Between GABAergic and Serotonergic Processes in the Dorsal Raphe Nucleus in the Control of REM Sleep and Wakefulness.- GABA-ergic Modulation of Pontine Cholinergic and Noradrenergic Neurons for REM Sleep Generation.- Involvement of GABAergic Mechanisms in the Laterodorsal and Pedunculopontine Tegmental Nuclei (LDT–PPT) in the Promotion of REM Sleep.- GABAergic Mechanisms in the Ventral Oral Pontine Tegmentum: The REM Sleep-Induction Site – in the Modulation of Sleep–Wake States.- The Role of GABAergic Modulation of Mesopontine Cholinergic Neurotransmission in Rapid Eye Movement (REM) Sleep.- Melatonin and Sleep: Possible Involvement of GABAergic Mechanisms.- GABA Involvement in the Circadian Regulation of Sleep.- Hypnotics.- Pathophysiology of Sleep Disorders.- Insomnia: Differential Diagnosis and Current Treatment Approach.- Zolpidem in the Treatment of Adult and Elderly Primary Insomnia Patients.- Efficacy and Safety of Zopiclone and Eszopiclone in the Treatment of Primary and Comorbid Insomnia.- Indiplon.-Polysomnographic and Clinical Assessment of Zaleplon for the Treatment of Primary Insomnia.

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