Overview

G Protein-Coupled Receptors, Part A, Volume 193 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field. G protein-coupled receptors (GPCRs) represent the largest class of cell surface proteins with an intricate involvement of nearly every physiological process in our body. Approximately, one third of the clinically prescribed medicines target GPCRs and the quest to improve the exiting GPCR-targeting therapeutics continues. These two volumes are focused on activation, signaling and regulation of GPCRs with specific examples of receptor systems and cellular processes.

Full Product Details

Author:   Arun K. Shukla (Indian Institute of Technology, Kanpur, India)
Publisher:   Elsevier Science & Technology
Imprint:   Academic Press Inc
Weight:   0.450kg
ISBN:  

9780323994316

ISBN 10:   0323994318
Pages:   230
Publication Date:   08 November 2022
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Preface Arun K. Shukla 1. Computational and experimental approaches to probe GPCR activation and signaling Paulina Dragan, Alessandro Atzei, Swapnil Ganesh Sanmukh and Dorota Latek 2. Adrenergic receptors in breast cancer Cecilia Pérez Piñero, Ezequiel Mariano Rivero, Lucía Gargiulo, María Sol Rodríguez, Carlos David Bruque, Ariana Bruzzone and Isabel Alicia Lüthy 3. Tools for adapting to a complex habitat: G-protein coupled receptors in Trichoderma Monika Schmoll and Wolfgang Hinterdobler 4. Targeting G protein-coupled receptors for alleviating neuropathic pain Poonam Kumari, Anubhav Yadav, Monika Patel and Prem N. Yadav 5. Crosstalk between neurons and glia through G-protein coupled receptors: Insights from Caenorhabditis elegans Pratima Pandey, Gazaldeep Kaur and Kavita Babu 6. Cardiovascular GPCR regulation by regulator of G protein signaling proteins Anastasios Lymperopoulos, Malka S. Suster and Jordana I. Borges 7. The interaction, mechanism and function of GPR158-RGS7 cross-talk Shradha Darira and Laurie P. Sutton 8. Taste GPCRs and their ligands Nitzan Dubovski, Fabrizio Fierro, Eitan Margulis, Yaron Ben Shoshan-Galeczki, Lior Peri and Masha Y. Niv 9. Palmitoylation and G-protein coupled receptors Georges Chaloub and Peter J. McCormick

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Author Information

Dr. Arun K. Shukla is a world leader in the field of GPCR biology and he is currently a Professor in the Department of Biological Sciences and Bioengineering at the Institute of Technology, Kanpur in India. Dr. Shukla’s research program is focused on understanding the structure, function and regulation of G protein-coupled receptors with a long-term of designing novel therapeutics with minimized side-effects.

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