Overview

Fundamentals of Redox Biology is a comprehensive guide to understanding the complex roles of cellular redox systems in biological processes and human health. Exploring the regulation, physiological functions, and pathological implications of reactive oxygen species (ROS) and free radicals, this book serves as an essential resource for students and professionals in biochemistry and related fields. It delves into the fundamentals of redox signaling, the impact of antioxidants on homeostasis, and the intricate balance between oxidative stress and disease development, including conditions like cancer and neurological disorders. This foundational text is invaluable for advancing knowledge in redox biology. In addition to providing a historical perspective on redox biology, the book examines how ROS influence epigenetic regulation and mitochondrial function, particularly in immune responses to infections. It also integrates discussions on the role of redox systems across multiple disciplines, making it relevant to cell biology, molecular biology, immunology, and beyond. With its detailed exploration of both theoretical and applied aspects, the book positions itself as a pivotal resource for understanding the mechanisms underlying redox balance and its broad applications in life sciences.

Full Product Details

Author:   Shyamal K Goswami (Professor (retired), School of Life Sciences, Jawaharlal Nehru University, New Delhi, India)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Weight:   0.450kg
ISBN:  

9780443223358

ISBN 10:   0443223351
Pages:   320
Publication Date:   08 December 2025
Audience:   Professional and scholarly ,  College/higher education ,  Professional & Vocational ,  Postgraduate, Research & Scholarly
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Section A: General topics 1. Free radicals and reactive species in human health and diseases: a historical perspective 2. Biochemistry of free radicals and reactive oxygen species 3. Tools and techniques for the detection and estimation of cellular ROS and other reactive species 4. Redox signaling 5. Role of ROS in genetic and epigenetic regulations 6. Cellular compartmentalization and its importance in the physiological functions of ROS 7. Antioxidants and their physiological roles in redox homeostasis Section B: Specialized topics 8. Role of ROS in metabolism: the cancer cell paradigm 9. ROS and cardiovascular and neurological disorders 10. ROS, the immune response, and its evasion by the pathogens 11. Iron/copper homeostasis, ROS and ferroptosis 12. Role of cellular redox in organismal biology: lessons from yeast, C elegans, Zebrafish, and Drosophila 13. Role of ROS in plant development and stress responses

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Author Information

Shyamal Goswami has a research career spanning 35 years. He has experience teaching in biochemistry, cellular and molecular biology and redox biology at the postgraduate level. He served as Associate Professor and Professor in the School of Life Sciences at Jawaharlal Nehru University, India, from 1998 to 2020. Prior to this he was a Research Assistant Professor in the Department of Anatomy and Cell Biology at the State University of New York-Health Science Centre at Brooklyn, New York, USA. Dr. Goswami has contributed numerous publications across his field. He also co-authored Protocols in Biochemistry and Clinical Biochemistry and co-edited Post-transcriptional Gene Regulation in Human Disease, both published by Academic Press/Elsevier. His main areas of research are cell signaling and gene expression in the cardiovascular system; redox biology of degenerative diseases; and signal scaffolds and cell functions.

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