Overview

This is an internationally recognized academic work that offers a scientific, in-depth, and interdisciplinary analysis of the foundations and clinical applications of personalized nutritional medicine. Written for health professionals, medical nutrition specialists, clinical nutritionists, researchers, and graduate students, this pioneering publication articulates the latest advances in functional nutrition, nutrigenomics, gut microbiota, and biochemical modulation, integrating them into clinical practice with technical rigor and evidence-based support. Based on approaches from systems biology, applied nutrigenetics, nutritional epigenetics, functional metabolic axes, and anti-inflammatory dietary strategies, the book provides tools for designing safe individualized protocols, advanced laboratory assessments, biomarker interpretation, and integration of molecular data. It also offers an in-depth discussion on the ethical boundaries, professional responsibility, and the risks of pseudoscience in functional practice, presenting a critical and up-to-date perspective on the use of genetic testing, high-cost supplements, and personalized interventions. Highlights: Evidence-based functional nutrition grounded in systems biology; Nutrigenomics and clinically relevant genetic polymorphisms (MTHFR, FTO, APOE); Epigenetic regulation through diet: methylation, microRNAs, histones; Composition and clinical impact of gut microbiota in obesity, depression, and autoimmune diseases; Anti-inflammatory diets, bioactive compounds, and functional foods; Hepatic detoxification, oxidative stress, and biotransformation pathways; Hormonal axes, neurotransmitters, and chrononutrition; Functional evaluation through advanced biomarkers and specialized laboratory tests; Ethical, personalized, and integrative clinical protocols; Future perspectives: artificial intelligence, biohacking, precision medicine. Written with clear scientific language, a didactic structure, and academic rigor, this book is essential reading for those working or intending to work at the intersection of personalized clinical nutrition, applied genomics, and scientifically grounded functional practices.

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