Overview
This book presents the state of the art of biostatistical methods and their applications in clinical oncology. Many methodologies established today in biostatistics have been brought about through its applications to the design and analysis of oncology clinical studies. This field of oncology, now in the midst of evolution owing to rapid advances in biotechnologies and cancer genomics, is becoming one of the most promising disease fields in the shift toward personalized medicine. Modern developments of diagnosis and therapeutics of cancer have also been continuously fueled by recent progress in establishing the infrastructure for conducting more complex, large-scale clinical trials and observational studies. The field of cancer clinical studies therefore will continue to provide many new statistical challenges that warrant further progress in the methodology and practice of biostatistics. This book provides a systematic coverage of various stages of cancer clinical studies. Topics from modern cancer clinical trials include phase I clinical trials for combination therapies, exploratory phase II trials with multiple endpoints/treatments, and confirmative biomarker-based phase III trials with interim monitoring and adaptation. It also covers important areas of cancer screening, prognostic analysis, and the analysis of large-scale molecular data in the era of big data.
Full Product Details
Author: Shigeyuki Matsui ,
John Crowley
Publisher: Springer Verlag, Singapore
Imprint: Springer Verlag, Singapore
Edition: Softcover reprint of the original 1st ed. 2017
Weight: 0.688kg
ISBN: 9789811090868
ISBN 10: 9811090866
Pages: 438
Publication Date: 04 September 2018
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Paperback
Publisher's Status: Active
Availability: Manufactured on demand
We will order this item for you from a manufactured on demand supplier.
Reviews
I strongly recommend that those statisticians working in the clinical oncology field check out these articles. Several were of use to me and I know that others will find them to be of use as well. (David E. Booth, Technometrics, Vol. 60 (3), 2018)
“I strongly recommend that those statisticians working in the clinical oncology field check out these articles. Several were of use to me and I know that others will find them to be of use as well.” (David E. Booth, Technometrics, Vol. 60 (3), 2018)
Author Information
Shigeyuki Matsui, Professor, Department of Biostatistics, Nagoya University Graduate School of Medicine, smatsui@med.nagoya-u.ac.jp, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan John Crowley, President and CEO, Cancer Research and Biostatistics, johnc@crab.org, 1730 Minor Ave STE 1900 Seattle, WA 98101-1468
