From Gene to Therapy: Understanding Human Disease through Genetics
Author:   Michael Dean
Publisher:   Morgan & Claypool Publishers
ISBN:  

9781615047710


Pages:   89
Publication Date:   30 September 2017
Format:   Hardback
Availability:   Available To Order   Availability explained
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From Gene to Therapy: Understanding Human Disease through Genetics


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Overview

Lecture provides an overview of the progress made in molecular medicine applying genetics and genomics to the understanding, diagnosis, and treatment of human diseases. Specifically, the methods for identifying genes involved in human diseases are described. Examples from 10 genes and diseases will be provided, drawing on the author's research. Topics include examples from simple Mendelian diseases, such as cystic fibrosis, inherited cancers, oncogenes activated by chromosomal translocations, host genes involved in infectious disease, genes identified via genomewide association studies, pathogens causing cancer, and gene families contributing to multiple diseases. For each example, historical details will be provided as background for readers to understand the context and process of the discoveries, technologies explained, and current understanding and treatment implications detailed.

Full Product Details

Author:   Michael Dean
Publisher:   Morgan & Claypool Publishers
Imprint:   Morgan & Claypool Publishers
Weight:   0.825kg
ISBN:  

9781615047710


ISBN 10:   1615047719
Pages:   89
Publication Date:   30 September 2017
Audience:   General/trade ,  General
Format:   Hardback
Publisher's Status:   Active
Availability:   Available To Order   Availability explained
We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately.

Table of Contents

Introduction Cystic Fibrosis: From Family Studies to Gene Mapping, Cloning, and Function to Therapy Cancer Genetics and Developmental Biology Chromosome Alterations and Cancer (MYC) Discovery of an AIDS Resistance Gene and Development of a Targeted Therapy (CCR5) Cancer in a Petri Dish: Discovery of an Oncogene (MET) Studying Populations of Cancer Patients From Cancer Virus to Cancer Vaccine: HPV and Cervical Cancer Sequencing the Tumor Genome ABC Genes: A Gene Family Causing Multiple Diseases An Eye on Macular Degeneration and Gene Therapy Conclusion References Author Biography

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Researcher in Cancer Genetics, Frederick, MD

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