Overview

This book covers the immunological and clinical aspects of central and peripheral nervous system inflammatory diseases characterized by myelin damage. Leading scientists in the field have summarized in short reviews the state of the art of neuroimmunology, with particular emphasis on basic aspects of the regulation of immune responses during demyelinating disorders. The volume will be helpful to neuroimmunologists, but also to clinicians which will find a clear and concise understanding of the main features of neuroinflammatory disease.

Full Product Details

Author:   Gianvito Martino ,  Luciano Adorini
Publisher:   Springer Verlag
Imprint:   Springer Verlag
Edition:   1999 ed.
Dimensions:   Width: 15.50cm , Height: 1.90cm , Length: 23.50cm
Weight:   1.430kg
ISBN:  

9788847000544

ISBN 10:   8847000548
Pages:   315
Publication Date:   01 March 1999
Audience:   College/higher education ,  General/trade ,  Postgraduate, Research & Scholarly ,  General
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

1 - Protective Versus Harmful Responses and Immune Regulation.- 2 - Antigen Recognition and Autoimmunity.- 3 - Assembly and Function of Immunoglobulins During B Cell Development.- 4 - Pathogenetic Mechanisms of Autoimmunity.- 5 - Adhesion Receptors Involved in Leukocyte Functions.- 6 - The Endothelium of the Brain Microvasculature and the Organization of Intercellular Junctions.- 7 - Chemokines and Chemokine Receptors.- 8 - Th1/Th2 Cytokine Network.- 9 - Lymphocyte Trafficking in the Central Nervous System.- 10 - Antigen Presentation in the Central Nervous System.- 11 - Myelination of the Central Nervous System.- 12 - Genomic Screening in Multiple Sclerosis.- 13 - MHC and Multiple Sclerosis.- 14 - Cytokine Genes in Multiple Sclerosis.- 15 - Adhesion Molecules and the and Blood-Brain-Barrier in Multiple Sclerosis.- 16 - Non-Myelin Antigen Autoreactivity in Multiple Sclerosis.- 17 - Myelin Antigen Autoreactivity in Multiple Sclerosis.- 18 - Inflammation and Multiple Sclerosis: a Close Interplay.- 19 - Magnetic Resonance and Blood-Brain Barrier Dysfunction in Multiple Sclerosis.- 20 - Immunotherapies for Multiple Sclerosis.- 21 - Animal Models of Demyelination of the Central Nervous System.- 22 - MHC and Non-MHC Genetics of Experimental Autoimmune Encephalomyelitis.- 23 - Genetics of Hereditary Neuropathies.- 24 - Immunopathogenetic Role of Anti-Neural Antibodies in Demyelinating Dysimmune Neuropathies.- 25 - Treatment of Inflammatory Demyelinating Polyneuropathy.

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