Overview

This concise monograph describes a variety of important reactions of iron in biological free-radical reactions. It presents both a chemical and a biochemical perspective of the topic, but at the same time unifies ideas where possible. Iron plays a key role in biological life processes, as a catalayst enabling us to use oxygen to generate the heat and chemical energy that drives life. When iron is not properly controlled within the body it can cause damage by making free radicals. The authors present a chemical and biomedical perspective of how reactions of iron complexes and free radicals may contribute to human health and disease, especially in reactions of oxygen and hydrogen peroxide.

Full Product Details

Author:   M. C. R. Symons (Visiting Professor, Department of Chemistry, DeMontfort University) ,  J. M. C. Gutteridge (Director, Oxygen Chemistry Laboratory, Directorate of Anaesthesia and Critical Care, Royal Brompton Hospital)
Publisher:   Oxford University Press
Imprint:   Oxford University Press
Dimensions:   Width: 16.10cm , Height: 1.90cm , Length: 24.20cm
Weight:   0.567kg
ISBN:  

9780198558927

ISBN 10:   0198558929
Pages:   254
Publication Date:   27 August 1998
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   In Print  
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

Table of Contents

Part 1 1: A dedication, some history, and a brief overview 2: Free radicals 3: Oxygen, hydrogen peroxide, and water 4: Iron valence states and ligands 5: The Fenton reaction Part 2 6: Natural iron ligands 7: Protection against superoxide, hydrogen peroxide, and ferrous ions 8: Superoxide, perioxides, and iron in biological systems 9: Iron and human diseases 10: Biological measurements and fingerprints of radical and related damage Appendix 1 - List of Fenton's publications Appendix 2 - 'Oxidation of Tartaric Acid in the Presence of Iron' Appendix 3 - Movement of Electrons and Protons Appendix 4 - The use of spectroscopic techniques in the detection of free-radical intermediates Appendix 5 - Reduction Potentials

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