Overview

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms.

Full Product Details

Author:   Gerald Litwack (Toluca Lake, North Hollywood, California, USA)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Volume:   79
Dimensions:   Width: 15.20cm , Height: 2.50cm , Length: 22.90cm
Weight:   0.750kg
ISBN:  

9780123742322

ISBN 10:   0123742323
Pages:   480
Publication Date:   21 November 2008
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

1. Folate-Mediated One-Carbon Metabolism Jennifer T. Fox and Patrick J. Stover 2. Mathematical Models of Folate-Mediated One-Carbon Metabolism H. Frederik Nijhout, Michael C. Reed and C.M. Ulrich 3. Folate Deprivation, the Methionine Cycle and Alzheimer!|s Disease Flaubert Tchantchou and Thomas B. Shea 4. Benefits and Risks of Folic Acid Supplementation Young-In Kim 5. Molecular Mechanisms of Adaptation to Folate Deficiency Ilan Ifergan and Yehuda G. Assaraf 6. Structure and Function of the Reduced Folate Carrier: A Paradigm of a Major Facilitator Superfamily Mammalian Nutrient Transporter Larry H. Matherly and Zhanjun Hou 7. Renal Conservation of Folates: Role of Folate Transport Proteins Vijaya L. Damaraju, Carol E. Cass and Michael B. Sawyer 8. Exploitation of the Folate Receptor in the Management of Cancer and Inflammatory Disease Christopher P. Leamon and Ann L. Jackman 9. Folate Receptor Expression in Pituitary Adenomas: Cellular and Molecular Analysis Chheng-Orn Evans, Congjun Yao, David Leborde and Nelson M. Oyesiku 10. Regulation of Human Dihydrofolate Reductase Activity and Expression Emine Ercikan Abali, Nancy E. Skacel, Hilal Celikkaya, Yi-Ching Hsieh 11. Catalysis of Methyl Group Transfers Involving Tetrahydrofolate and B12 Stephen W. Ragsdale 12. Methyltetrahydrofolate in Folate-Binding Protein Glycine N-Methyltransferase Zigmund Luka 13. Mechanism-Based Inhibitors of Folylpoly-fx-glutamate Synthetase and fx-Glutamyl Hydrolase: Control of Folylpoly-fx-glutamate Homeostasis as a Drug Target James K. Coward and John J. McGuire 14. Methylenetetrahydrofolate Reductase, Common Polymorphisms and Relation to Disease Philip Thomas and Michael Fenech 15. Mitochondrial Methylenetetrahydrofolate Dehydrogenase, Methenyltetrahydrofolate Cyclohydrolase and Formyltetrahydrofolate Synthetases Karen E. Christensen and Robert E. MacKenzie 16. The Structure and Mechanism of 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase Jeremy P. Derrick

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Author Information

Trained in biochemistry at the University of Wisconsin, Madison, Dr. Litwack worked on enzymology and the effects of hormones on enzyme systems. Then he was a Postdoctoral Fellow of the National Foundation for Infantile Paralysis at the Biochemical Institute of the Sorbonne in Paris. Dr. Litwack's first position was as Assistant Professor of Biochemistry at Rutgers University in 1954. Six years later, he joined the University of Pennsylvania as associate professor and four years later went to the Fels Institute for Cancer Research and Molecular Biology, as full professor, eventually becoming Deputy Director of the Institute. In 1991, he accepted the Chair of Pharmacology at Thomas Jefferson University where he is also Deputy Director of the Jefferson Cancer Institute and Associate Director for Basic Science in the Jefferson Cancer Center. Dr. Litwack's work has been in the area of mechanisms of steroid receptor action involving especially the glucocorticoid and mineralocorticoid receptors, immunophi.

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