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Author:   David A. D. Parry ,  Pradeep K. Luther
Publisher:   Springer Nature Switzerland AG
Imprint:   Springer Nature Switzerland AG
Edition:   Second Edition 2026
ISBN:  

9783032052728

ISBN 10:   3032052726
Pages:   558
Publication Date:   21 January 2026
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Chapter 1. Sequence Prediction, Structural Modelling and the Challenges of Plasticity in Coiled Coils.- Chapter 2. Structure of the Myosin Thick Filaments In Muscle.- Chapter 3. The Structural Role of Tropomyosin In Regulating Thin Filament Activation of Actin-Myosin Interaction.- Chapter 4. Structural Biology of Actin: Interplay Between Molecular Assembly, Conformational Polymorphism and ATPase.- Chapter 5. Structural and Functional Elements Of The Epidermal Appendages In Birds and Reptiles: Conformations And Modes of Assembly of the Constituent b-Filaments And Keratin Intermediate Filaments (IF).- Chapter 6. Insights into the Structure of Intermediate Filaments.- Chapter 7. Intermediate Filaments: structure-mechanics crosstalk.- Chapter 8. The Fibrillar Collagens of Bony Fish: Genes, Proteins And Biomedical Applications.- Chapter 9. Comparative Study of the Positions of Glycosylated Residues In The Chains Of Fibril-Forming Collagens And The Role That These Residues Play in Axial and Lateral Assembly.- Chapter 10. Collagen Mechanics.- Chapter 11. Collagen in Fibrotic Diseases.- Chapter 12. The Impact of Ageing on Fibrillar Collagen.- Chapter 13. Fibrin as a Versatile Fibrous Biopolymer.- Chapter 14. Biology and Molecular Structure of the a-Fibrous Silks in Bees, Ants, Wasps and Hornets (Hymenoptera).- Chapter 15. Designability of a-Helical Protein Filaments.- Chapter 16. The Many lives of a Single Sequence: Functional Plasticity through Amyloid Polymorphism.

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Author Information

David A. D. Parry has been active in X-ray diffraction, electron microscopy and sequence analysis of fibrous proteins for nearly 60 years. His scientific contributions at Massey University have been recognised by the award of six medals, Companionship of the New Zealand Order of Merit and election to Fellowship of the Royal Society of New Zealand. He has been President of the International Union for Pure and Applied Biophysics (IUPAB) and Vice President of the International Council for Science (ICSU). He has contributed 246 scientific papers and has written and/or edited seven books and six special Journal issues. Pradeep K. Luther is a structural biologist working on cardiac and skeletal muscle and has used electron tomography and cryo-electron tomography to study the structure of thick filaments, the Z-band and the M-band. His research has utilised the recent advances made in cryo-electron microscopy and image processing, and this has enabled new insights to be gained into the structure and working of the sarcomere and the effects that drugs designed to tackle disease have on this important motile element. Luther is at the National Heart and Lung Institute, Imperial College London.

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