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Author:   Marc Daeron ,  Falk Nimmerjahn
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   Softcover reprint of the original 1st ed. 2014
Volume:   382
Dimensions:   Width: 15.50cm , Height: 2.30cm , Length: 23.50cm
Weight:   6.613kg
ISBN:  

9783319379098

ISBN 10:   3319379097
Pages:   424
Publication Date:   23 August 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Part I : Old and new FcRs   Hiromi Kubagawa, Yoshiki Kubagawa, Dewitt Jones, Tahseen H. Nasti, Mark Walter, and Kazuhito Honjo The Old but New IgM Fc Receptor (FcμR)   F.J. Li, W.J. Won, E.J. Becker Jr., J.L. Easlick, E. Tabengwa, R. Li, M. Shakhmatov, P.D. Burrows, and R.S. Davis Emerging Roles for FCRL Family Members in Lymphocyte Biology and Disease   Leo C. James Intracellular antibody immunity and the cytosolic Fc receptor TRIM21     Part II: FcR signaling   Anna Niarakis, Yacine Bounab, Luca Grieco, Roman Roncagalli, Jérôme Garin, Bernard Malissen, Marc Daëron, Denis Thieffry Computational modeling of the main signaling pathways involved in mast cell activation   Tarik Attout, Andres Floto and Pierre Launay Calcium channels in FcR signaling   Marcel Kuhny, Carolin N. Zorn, and Michael Huber Regulation of FcεRI signaling by lipid phosphatases     Part III: FcR biology   Marc Daëron Fc Receptors as Adaptive Immunoreceptors   Jerrard M Hayes, Eoin FJ Cosgrave, Weston B Struwe, Mark Wormald, Gavin P. Davey, Roy Jefferis, Pauline M Rudd Glycosylation and Fc Receptors   Birgitta Heyman Antibodies as natural adjuvants   Sanae Ben Mkaddem, Ivy Christou, Elisabetta Rossato, Laureline Berthelot, Agnès Lehuen and Renato C. Monteiro IgA, IgA receptors and their anti-inflammatory properties   Stylianos Bournazos, David J. DiLillo and Jeffrey V. Ravetch Humanized mice to study FcγR function   Dilip K. Challa, Ramraj Velmurugan, Raimund J. Ober and E. Sally Ward FcRn: from molecular interactions to regulation of IgG pharmacokinetics and functions.     Part IV: FcRs and disease   Xinrui Li, Andrew W Gibson and Robert P Kimberly Human FcR polymorphism and disease.   Hanane el Bannoudi, Andreea Ioan-Facsinay and René E. M. Toes Bridging auto-antibodies and arthritis; the role of Fc Receptors   P. Mark Hogarth, Jessica C. Anania, Bruce D. Wines The FcγR of humans and non-human primates and their interaction with IgG:  Implications for induction of inflammation, resistance to infection and the use of therapeutic monoclonal antibodies     Part V: FcRs and therapeutic antibodies   Ann L White, Stephen A Beers and Mark S. Cragg FcgRIIB as a key determinant of agonistic antibody efficacy                Jantine E. Bakema and Marjolein van Egmond Fc receptor dependent mechanisms of monoclonal antibody therapy of cancer; professionals at work   Sybille Böhm, Daniela Kao and Falk Nimmerjahn Sweet and Sour: The role of glycosylation for the anti-inflammatory activity of immunoglobulin G

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