Overview

In this book emerging questions of current glutamate research are addressed and new pathways which glutamte research may take in the future discussed. Since glutamate antagonists are still the major hope for the therapy of neurodegenerative disorders in humans, research activities dedicated towards the development of such novel drugs are the focus of public attention. The book comments on the most recent discoveries in the field of neuroprotection and neurodegeneration.

Full Product Details

Author:   Peter H. Seeburg ,  Iris Bresink ,  Lechoslaw Turski
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 1998
Volume:   23
Dimensions:   Width: 14.80cm , Height: 1.20cm , Length: 21.00cm
Weight:   0.298kg
ISBN:  

9783662035986

ISBN 10:   3662035987
Pages:   210
Publication Date:   08 December 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1 Glutamate Receptor Channels, RNA Editing, and Epilepsy.- 2 Regulation of Glutamate Receptor Gene Expression in Global Ischemia.- 3 Factors Regulating Excitotoxic Neurodegeneration: The Role of Calcium and the Mitochondria.- 4 Excitotoxicity, Genetics, and Neurodegeneration in Amyotrophic Lateral Sclerosis.- 5 NO-NMDA Receptor Interactions: A Neuromolecular Approach to Novel Therapeutics.- 6 Glutamate in Neurodegenerative Disorders: Phenotype Resulting from Decreased Expression of AMPA Receptor GIuR-B Subunit mRNA in Rats.- 7 Quantitative Estimation of NMDA Receptor-Mediated Ca2+ Entry in Central Neurons.- 8 Calcium Permeability of Glutamate-Gated Channels in the CNS: Functional Role of the Ca2+-Permeable AMPA Receptor Channels.- 9 Localisation and Surface Expression of the AMPA Receptor Subunit GluR1 Using Green Fluorescent Protein and Anti-Peptide Antibodies.- 10 Input- and Output-Specific Segregation of Amino Acid Neurotransmitter Receptors on the Surface of Central Neurones.- Previous Volumes Published in this Series.

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