Ex Vivo Engineering of the Tumor Microenvironment
Author:   Amir R. Aref ,  David Barbie
Publisher:   Birkhauser Verlag AG
Edition:   1st ed. 2017
ISBN:  

9783319453958


Pages:   135
Publication Date:   16 December 2016
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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Ex Vivo Engineering of the Tumor Microenvironment


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Overview

This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time.

Full Product Details

Author:   Amir R. Aref ,  David Barbie
Publisher:   Birkhauser Verlag AG
Imprint:   Birkhauser Verlag AG
Edition:   1st ed. 2017
Dimensions:   Width: 15.50cm , Height: 1.00cm , Length: 23.50cm
Weight:   3.495kg
ISBN:  

9783319453958


ISBN 10:   3319453955
Pages:   135
Publication Date:   16 December 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1.Introduction to Ex Vivo Cancer Models.- 2.Patient-derived Xenografts in Oncology.- 3.Organoid Culture: Applications in Development and Cancer.- 4. Microfluidics and future of cancer diagnostics.- 5.Advancing techniques and insights in circulating tumor cell (CTC) research.- 6.The Cancer Secretome.- 7.An overview of the tumor microenvironments and future of cancer therapy.  

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Author Information

Amir R. Aref, PhD, is Instructor, Dana-Farber Cancer Institute, Harvard Medical School.

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