Estrogen Receptors: Mechanisms, Structure & Role in Disease
Author:   George Chen
Publisher:   Nova Science Publishers Inc
ISBN:  

9781622570980


Pages:   178
Publication Date:   17 January 2013
Format:   Hardback
Availability:   Available To Order   Availability explained
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Estrogen Receptors: Mechanisms, Structure & Role in Disease


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Overview

Oestrogen receptors (ER) are emerging as important molecules involved in the variety of physiological and pathological activities. There are two classic oestrogen receptors: alpha and beta. Different cells and tissues have shown divergent responses to these two oestrogen receptors. While we are starting to understand the interaction between oestrogen receptors and its ligands contributes to the development of various diseases, the discovery of sub-isoforms of oestrogen receptor alpha and beta has further complicated the mechanism of oestrogen receptors. Nevertheless, continuing efforts in the study of oestrogen receptors have helped us to define their roles in diseases and to develop novel therapies against these disorders. The 11 chapters in this book are the excellent evidence to summarise our efforts in this direction. This book should be of great value to not only clinicians and medical students interested in oestrogen/ER-related diseases but also basic scientists working in the field of estrogens/ERs.

Full Product Details

Author:   George Chen
Publisher:   Nova Science Publishers Inc
Imprint:   Nova Science Publishers Inc
Weight:   0.484kg
ISBN:  

9781622570980


ISBN 10:   1622570987
Pages:   178
Publication Date:   17 January 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Available To Order   Availability explained
We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately.

Table of Contents

Preface: Continuing efforts needed to decode the complexity of estrogen receptors; Estrogen receptors: mechanisms, structure & role in endometriosis; Mechanisms of Estrogen Receptor Extranuclear Signaling In Human Diseases; Function, expression, & deterction of estrogen receptor isoforms in normal & malignant tissues; Regulation of neuropeptidases involved in reproductive physiology by estradiol; Endocrine therapy options in premenopausal women with oestrogen receptor positive advanced breast cancer; Nongenomic action of estrogen receptor in breast cancer; Triple negative breast cancer: clinicopathological charateristics, challenges & therapy.

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