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Author:   William B. Coleman ,  Gregory J. Tsongalis
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Dimensions:   Width: 21.60cm , Height: 2.70cm , Length: 27.90cm
Weight:   1.550kg
ISBN:  

9780123744180

ISBN 10:   0123744180
Pages:   462
Publication Date:   09 February 2010
Audience:   College/higher education ,  Tertiary & Higher Education
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
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Table of Contents

PART I Essential Pathology - Mechanisms of Disease Chapter 1 Cell Injury, Cell Death, and Cellular Adaptation John J. Lemasters, M.D., Ph.D. Chapter 2 Acute and Chronic Inflammation Vladislav Dolgachev, Ph.D. and Nicholas W. Lukacs, Ph.D. Chapter 3 Infection and Host Response Sheldon M. Campbell, M.D., Ph.D. and Margret Oethinger, M.D.,Ph.D. Chapter 4 Neoplasia William B. Coleman, Ph.D., and Tara Rubinas, M.D. PART II Concepts in Molecular Biology and Genetics Chapter 5 Basic Concepts in Human Molecular Genetics W. Edward Highsmith, Ph.D., and Kara A. Mensink, M.S., C.G.C. Chapter 6 The Human Genome: Implications for the Understanding of Human Disease William B. Coleman, Ph.D, Gregory J. Tsongalis, Ph.D. and Ashley Rivenbark, M.D. Chapter 7 The Human Transcriptome: Implications for the Understanding of Human Disease Reinhold Schafer, Ph.D., Matthias E. Futschik, Ph.D., Wolfgang Kemmner, Ph.D., and Christine Sers, Ph.D. Chapter 8 The Human Epigenome: Implications for the Understanding of Human Disease Manel Esteller, Ph.D. and Maria Berdasco, Ph.D. Chapter 9 The Human Proteome: Implications for the Understanding of Human Disease Lance Liotta, Ph.D., Virginia Espina, Claudia Fredolini, Weidong Zhou, and Emanuel Petricoin Chapter 10 Integrative Systems Biology: Implications for the Understanding of Human Disease M. Michael Barmada, Ph.D. and David C. Whitcomb PART III Principles and Practice of Molecular Pathology Chapter 11 Pathology: The Clinical Description of Human Disease William K. Funkhouser, M.D., Ph.D. Chapter 12 Molecular Pathogenesis: The Biological Basis of Human Disease William B. Coleman, Ph.D, and Gregory J. Tsongalis, Ph.D. Chapter 13 Integration of Molecular and Cellular Pathogenesis Jason H. Moore, Ph.D., and C. Harker Rhodes, M.D. PART IV Molecular Pathology of Human Disease Chapter 14 Molecular Basis of Cardiovascular Disease Avrum I. Gotlieb, M.D.C.M. and Amber Chang Liu Chapter 15 Molecular Basis of Hemostatic and Thrombotic Diseases Nigel S. Key, M.D., and Alice Ma, M.D. Chapter 16 Molecular Basis of Lymphoid and Myeloid Diseases Dong-Er Zhang, Ph.D. and Joseph Biggs, Ph.D. Chapter 17 Molecular Basis of Diseases of Immunity David O. Beenhouwer, Ph.D. Chapter 18 Molecular Basis of Pulmonary Disease Dani S. Zander, M.D., and Carol Farver, M.D. Chapter Chapter 19 Molecular Basis of Diseases of the Gastrointestinal Tract Antonio Sepulveda, M.D., Ph.D. and Dara L. Aisner, M.D., Ph.D. Chapter 20 Molecular Basis of Liver Disease Satdarshan P. Singh Monga, M.D. and Jaideep Behari, M.D. Chapter 21 Molecular Basis of Diseases of the Exocrine Pancreas Markus M. Lerch, M.D. Chapter 22 Molecular Basis of Diseases of the Endocrine System Malcolm M. Martin, M.D., Arlene L. Martin, M.D., Alan L.Y. Pang, Ph.D., and Wai-Yee Chan, Ph.D. Chapter 23 Molecular Basis of Gynecologic Diseases Samuel Chi-ho Mok, Ph.D., Kwong-Kwok Wong, Ph.D., Karen Lu, M.D., Karl Munger, Ph.D., and Zoltan Nagymanyoki, Ph.D. Chapter 24 Molecular Pathogenesis of Diseases of the Kidney Amy K. Mottl, M.D., M.P.H., and Carla Nester, M.D., M.S.A. Chapter 25 Molecular Basis of Prostate Disease William G. Nelson, M.D., Ph.D., Angelo M. De Marzo, M.D., Ph.D., and Carlise R. Bethel, M.D., Ph.D. Chapter 26 Molecular Basis of Breast Disease Christos Sotiriou, M.D., Ph.D., Natasha Snoj, Phuong Dinh, and Philippe Bedard Translational Research Unit, Jules Bordet Institute, Universite Libre de Bruxelles, Brussels, Belgium Chapter 27 Molecular Basis of Skin Disease John A. McGrath, Ph.D., and Vesarat Wessagowit, M.D., Ph.D. Chapter 28 Molecular Basis of Diseases of the Nervous System Joshua A. Sonnen, M.D., C. Dirk Keene, M.D., Robert F. Hevner, M.D., and Thomas J. Montine, M.D., Ph.D. PART V Practice of Molecular Medicine Chapter 29 Molecular Diagnosis of Human Disease Grant Bullock, M.D., Ph.D., and Lawrence M. Silverman, Ph.D. Chapter 30 Molecular Assessment of Human Disease in the Clinical Laboratory Gregory J. Tsongalis, Ph.D. and Joel A. Lefferts, M.D. Chapter 31 Pharmacogenomics and Personalized Medicine in the Treatment of Human Disease Gregory J. Tsongalis, Ph.D. and Hong Kee Lee, Ph.D.

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Author Information

William B. Coleman, PhD is Professor of Pathology and Laboratory Medicine and Director of Graduate Studies for the Molecular and Cellular Pathology Graduate Program at the University of North Carolina School of Medicine (Chapel Hill, NC). Dr. Coleman is co-director of the UNC Program in Translational Medicine, and co-director of the Environmental Pathology Predoctoral and Postdoctoral Training Program. In addition, he is affiliated with the Curriculum in Toxicology and is a member of the UNC Lineberger Comprehensive Cancer Center. Dr. Coleman is actively involved in teaching biomedical graduate students and is a three-time recipient of the Joe W. Grisham Award for Excellence in Graduate Student Teaching from the Molecular and Cellular Pathology graduate students at UNC-Chapel Hill. Dr. Coleman is active in the leadership of the American Society for Investigative Pathology, and is a member of the American Association for Cancer Research. He serves on the editorial boards of Clinica Chimica Acta, The American Journal of Pathology, Experimental and Molecular Pathology, Archives of Pathology and Laboratory Medicine, and Laboratory Investigation, and has served as an ad hoc reviewer for 48 other journals. Dr. Coleman's major research interests are in the molecular pathogenesis of human cancers, with a specific interest in breast cancer epigenetics, liver carcinogenesis, and lung cancer biology. His research has been funded by the NIH/NCI, The Susan G. Komen Breast Cancer Foundation, Friends for an Earlier Breast Cancer Test, and the UNC Lineberger Comprehensive Cancer Center. Dr. Coleman is the author of over 100 original research articles, reviews, and book chapters. In addition, Dr. Coleman has co-edited or co-authored six books on topics related to molecular pathology, molecular diagnostics, and the molecular pathogenesis of human cancer. Gregory J. Tsongalis, Ph.D., H.C.L.D., C.C. is Professor of Pathology, Director, Molecular Pathology, and Co-Director Translational Research Program, Department of Pathology, Dartmouth Hitchcock Medical Center and The Audrey and Theodor Geisel School of Medicine at Dartmouth, Lebanon, NH, USA

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