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Author:   D. V. Ablashi ,  A. T. Huang ,  J. S. Pagano ,  G. R. Pearson
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   1991 ed.
Volume:   24
Dimensions:   Width: 15.50cm , Height: 2.60cm , Length: 23.50cm
Weight:   1.940kg
ISBN:  

9780896032217

ISBN 10:   0896032213
Pages:   455
Publication Date:   11 November 1991
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

I. Molecular Biology of EBV.- Replication of the Epstein-Barr Virus in Lymphoid and Epithelial Cells.- The Productive Cycle Defect in Raji EBV is Not Solely Due to Absence of the BALF2 Gene.- Interference of EBNA-1 Binding to ori -P by Cellular Proteins (Anti-EBNA1).- How ZEBRA, a Weak Transactivator, Exerts Strong Biologic Effects.- EBNA-2 Transactivation of CD23.- EBNA-2 Transactivation of LMP1.- A New Lymphoid-Specific Epstein-Barr Virus Enhancer Is Transactivated by EBNA-2.- Transcriptional Regulation of an Epstein-Barr Virus Nuclear Antigen Gene Promoter.- EBNA-2 Influences Promoter Function in Burkitt Lymphoma Cells.- Functional Characterization of Epstein-Barr Virus DNA Polymerase by In Vitro Transcription-Translation of Cloned Genes.- Epstein-Barr Virus Recombinants: Use of Positive Selection Markers to Rescue Mutants in EBV Negative B Lymphoma Cells.- Characterization of EBV DNase Related Transcripts.- The PstI- Repeats of the Epstein-Ban Virus Encode a Protein with a Molecular Weight between 115,000 and 140,000.- The EBV BRLF1 Protein Has Sequence and Functional Similarity with the C-myb Oncogene.- Heterodimers of the ZEBRA and fos Basic Domains Bind DNA with the Specificity of ZEBRA.- Relationship of the EBV Lytic Activator Zta to the bZIP Family of Cellular Transactivators.- Trans-Regulation of the Early MS Gene of EBV and Its Depen-dence on the Host Cell.- Induction and Regulation of Expression of the Epstein-Barr Virus DNA Polymerase Gene.- Recombinant EBV Antigens and Their Diagnostic Value.- Epstein-Barr Virus Associated Histio-Lymphoproliferative Syndromes in Two European Families.- II. Pathobiology of EBV.- Role of Cytokines in EBV-Infected Cell Growth.- Epstein-Barr Virus Variants at Mucosal Surfaces.- Epstein-Barr Virus Infection and Monokine Synthesis.- Transcription from Bam HI A in NPC.- Characterisation of the Novel “18.8” Family of Transcripts from NPC Tumours.- EBER1 Small Nuclear RNA in Malignancy: A Morphologically Distinctive Target for Detection of EBV in Formalin-Fixed Paraffin-Embedded Specimens.- Tumorigenicity and Organization of the Terminal Region of the Epstein-Barr Virus (EBV) Genome in LCLs Derived from Carcinogen-Treated Lymphocytes.- Expression of EBNA2 and an EBNA5 Protein from Alternatively Spliced mRNA’s.- III. Immunology of EBV.- EBV Humoral Immunology: 1966-1990.- The Role of EBNA Proteins as a Target for EBV-Specific T Cell Lysis.- Role of the Epstein-Barr Virus (EBV) Glycoprotein gp350 as a Target Antigen for EBV-Specific Cellular Killing.- Mapping of B and T Cell Epitopes on the Epstein-Barr Virus Receptor Ligand gp340: A Candidate Subunit Vaccine.- Identification of T Helper Cell Epitopes on gp 340.- Reactivity of EBV Type A-Specific Cytotoxic T-Cells.- DNA Sequence Variation in EBV-Encoded T-Cell Epitopes.- Recombinant Adenoviruses Which Express the EBV Major Membrane Antigen gp340/220 Induce Persistent EBVNeutralizing Antibodies in Rabbits.- Inhibition of the EBV Lytic Cycle by Sequence Specific Antisense Oligonucleotides.- IV. EBV Associated Lymphoproliferative Disorders.- Advances in the Understanding of EBV Associated Lympho-proliferative Disorders.- The Association of Epstein-Barr Virus with Lymphoproliferative Disorders: A Re-Evaluation Using the Polymerase Chain Reaction.- Absence of EBV in Reed-Sternberg Cells in Many Cases of Hodgkin’s Disease.- EBV and Granular Lymphocytes Proliferation.- EBV Transmission and Expression Among Patients with PTLD.- SCID Mouse Model of Virus-Induced Lymphomagenesis of Immunodeficient Humans.- Patients with Psoriasis Have High SerumReactivity with EBNA2B.- EBV Activation by Anti-IgG-Triggered, Second Messenger Pathways.- V. Advances in NPC.- Nasopharyngeal Carcinoma:1990.- In Situ Analysis of Epstein-Barr Viral Expression in Nasopharyngeal Carcinoma.- Interaction of EBV Genes with Human Epithelial Cells.- Studies on the Terminal Protein I (TP1) of the Epstein-Barr Virus and the Anti-TP Immune Response in Humans.- Diagnosis of Nasopharyngeal Carcinoma Using the Epstein-Barr Virus Coded Alkaline DNase Membrane Antigen and Thymidine Kinase.- Detection of Anti-Epstein Barr Virus Transactivator (ZEBRA) Antibodies in Sera from Patients with Nasopharyngeal Carcinoma.- EBV pp58 DNase Expressed in the Baculovirus System May Improve the Diagnosis of NPC.- Efficacy of Exfoliative Cytology in Diagnosis of Nasopharyngeal Carcinoma.- Neoadjuvant Approach with Bleomycin, Epirubicin and Cisplaten in the Treatment of Locally Advanced UCNT.- VI. Clinical Aspects of NPC.- Pathogenesis of Nasopharyngeal Carcinoma.- EBV Genome Oranization in Lymphoblastoid Cell Lines Established Following Enhancement with Aflatoxin B1 and Relevance to Nasopharyngeal Carcinoma.- Preliminary Results of HLA Class I and Class II Antigens in Chinese with Nasopharyngeal Carcinoma.- Radiation Therapy of Nasopharyngeal Cancer in Taiwan University Hospital 1958-1989.- 417 Chemotherapy in Undifferentiated Type Nasopharyngeal Carci-noma (UCNT).- Neoadjuvant Chemotherapy Plus Radiotherapy Versus Radiotherapy Alone in Nasopharyngeal Cancer.- The Role of Surgery in the Management of Recurrent Primary Nasopharyngeal Carcinoma.- Randomized Controlled Studies on Immunotherapy of Nasopharyngeal Carcinoma with OK-432.- A Preliminary Study on the Immunogenicity in Rabbits and in Human Volunteers: Recombinant Vaccinia Virus Expressing Epstein-Barr VirusMembrane Antigen.- List of Participants.

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...can be recommended as containing a wealth of source material, not otherwise easily accessible.-Reviews in Medical Virology

...can be recommended as containing a wealth of source material, not otherwise easily accessible. - Reviews in Medical Virology

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