Overview

This book reviews the current state of epigenetics and proteomics of leukemia and introduces the methods that are important to process and evaluate these factors in leukemia. In particular, epigenetic modifiers and their inhibitors in leukemia treatment as well as approaches to the epigenetic treatment of leukemia are covered. Various computational methods for proteome analysis are also described in detail, including 2DE fractionation and visualization, proteomic data processing, image acquisition and data anlaysis, and more. Protein localization in leukemia is also covered, in addition to the future of leukemia therapy. Epigenetics and Proteomics of Leukemia is an ideal book for advanced biomedical scientists and students, medical doctors and students, bioinformatics and health informatics researchers, computational biologists, structural biologists, systems biologists, and bioengineers.

Full Product Details

Author:   R¯uta Navakauskien˙e ,  Dalius Navakauskas ,  Veronika Borutinskait˙e ,  Dalius Matuzevi˘cius
Publisher:   Springer Nature Switzerland AG
Imprint:   Springer Nature Switzerland AG
Edition:   1st ed. 2021
Weight:   0.863kg
ISBN:  

9783030687076

ISBN 10:   3030687074
Pages:   406
Publication Date:   15 September 2021
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Overview / Introduction Section I: Epigenetics in Leukemia Chapter 1: Genetic and Epigenetic Alterations in Leukemia Chapter 2: Epigenetic Modifiers and Their Inhibitors in Leukemia Treatment Chapter 3: Chromatin Remodeling during Leukemia Cell Proliferation and Differentiation DNA Methylation and Epigenetic Regulation Chromatin Functional Regulation by Histone Modification Chapter 4: Approaches to Epigenetic Treatment of Leukemia Section II: Proteomics in Leukemia Chapter 5: Proteome in Leukemic vs. Differentiated Leukemia Cells Chapter 6: Protein Phosphorylation in Leukemia Chapter 7: Computational Methods for Proteome Analysis 2DE Fractionation and Visualization Proteomic Data Processing Proteomic Data Analysis Image Acquisition and Data Analysis Section III: Protein Localization in Leukemia Chapter 8: Protein Translocation into the Nucleus during Leukemia Cell Differentiation Chapter 9: Protein Visualization in Leukemic Cells Chapter 10: Computational Methods for Protein Localization Estimation Fluorescent Image Processing Fluorescent Image Acquisition and Analysis Section IV: Future Therapy in Leukemia

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Author Information

Rūta NAVAKAUSKIENĖ, Dr. Prof.Department of Molecular Cell Biology, Institute of Biochemistry, Life Sciences Center, Vilnius University, Sauletekio av. 7, LT-10257 Vilnius, Lithuania Dalius NAVAKAUSKAS, Dr. Prof.Department of Electronic Systems, Faculty of Electronics, Vilnius Gediminas Technical University, Naugarduko st. 41-426, LT-03227 Vilnius, Lithuania Veronika BORUTINSKAITĖ, Dr.Department of Molecular Cell Biology, Institute of Biochemistry, Life Sciences Center, Vilnius University, Sauletekio av. 7, LT-10257 Vilnius, Lithuania Dalius MATUZEVIČIUS, Dr. Assoc. Prof.Department of Electronic Systems, Faculty of Electronics, Vilnius Gediminas Technical University, Naugarduko st. 41-413, LT-03227 Vilnius, Lithuania

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