Overview

Epigenetic Technological Applications is a compilation of state-of-the-art technologies involved in epigenetic research. Epigenetics is an exciting new field of biology research, and many technologies are invented and developed specifically for epigenetics study. With chapters covering the latest developments in crystallography, computational modeling, the uses of histones, and more, Epigenetic Technological Applications addresses the question of how these new ideas, procedures, and innovations can be applied to current epigenetics research, and how they can keep pushing discovery forward and beyond the epigenetic realm.

Full Product Details

Author:   Yujun George Zheng (Associate Professor, Department of Pharmaceutical and Biomedical Sciences, University of Georgia)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Dimensions:   Width: 19.10cm , Height: 3.00cm , Length: 23.50cm
Weight:   1.270kg
ISBN:  

9780128010808

ISBN 10:   0128010800
Pages:   516
Publication Date:   28 July 2015
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Preface 1. Introduction of the Epigenetic Technologies 2. Technologies for the Measurement and Mapping of Genomic 5-methylcytosine and 5-hydroxymethylcytosine 3. Technologies to Map DNA 5hC and 5fC and 5caC 4. Application of Mass Spectrometry in Translational Epigenetics 5. Techniques Analyzing Chromatin Modifications at Specific Single Loci 6.  Comprehensive Analysis of Mammalian Linker-histone Variants and Their Mutants 7. Crystallography-based Mechanistic Insights into Epigenetic Regulation 8. Chemical and Genetic Approaches to Study Histone Modifications 9. Peptide Microarrays for Profiling of Epigenetic Targets 10. Current Methods for Methylome Profiling 11. Bioinformatics and Biostatistics for Mining Epigenetic Disease Markers and Targets 12. Computational Modeling to Elucidate Molecular Mechanisms of Epigenetic Memory 13. DNA Methyltransferase Inhibitors for Cancer Therapy 14. Histone Acetyltransferases: Enzymes, Assays, and Inhibitors 15. In Vitro Histone Deacetylase Activity Screening: Making a Case for Better Assays 16. Enzymatic Assays of Histone Methyltransferase Enzymes 17. Histone Methyltransferase Inhibitors for Cancer Therapy 18. Discovery of Histone Demethylase Inhibitors 19. Fluorescent Technologies in Studying Dynamics of Histone Modification 20. Animal Model Study of Epigenetic Inhibitors

Reviews

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions