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Author:   Manfred P. Schneider
Publisher:   Springer
Imprint:   Kluwer Academic Publishers
Edition:   1986 ed.
Volume:   178
Dimensions:   Width: 15.50cm , Height: 2.50cm , Length: 23.50cm
Weight:   1.750kg
ISBN:  

9789027722676

ISBN 10:   9027722676
Pages:   422
Publication Date:   30 June 1986
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Lectures.- Baker’s yeast mediated preparation of carbohydrate-like chiral synthons.- Alcohol dehydrogenase catalysed oxidoreduction reactions in organic chemistry.- On the use of viologen dyes for stereospecific bioreduction.- Approaches to chiral building blocks for natural product synthesis.- Use of microorganisms for the resolution of synthetically useful bicyclo[ 3.2.0] hept-2-en-6-ones.- The scope of biocatalysts in organic chemical processing.- Enantioselective synthesis of biologically active cyclopentanoids via enzyme catalysed asymmetric reactions.- Creation of novel chiral synthons with pig liver esterase: application to natural product synthesis and the substrate recognition.- Application of microbial transformations in the total synthesis of natural products.- Approaches to chiral building blocks for natural products synthesis.- Synthesis of enantiomerically pure unnatural compounds via non-biomimetic homoaldol reactions.- Aldolases as catalysts in organic synthesis.- Immobilised redox enzymes and their use as catalysts for fine chemical synthesis.- Applications of microbes and microbial enzymes in environmental control and organic synthesis.- Synthesis of chirally labelled substrates using enzymes.- Synthesis of L-amino acids by isolated enzymes and microorganisms.- Development of an enzyme reactor for food chemistry.- Preparation and properties of semisynthetic flavoenzymes.- The study and redesign of enzymes by protein engineering.- Evolutionary guidance and the engineering of enzymes.- Posters.- Baker’s yeast mediated synthesis of protected ?-hydroxyaldehydes.- Enantioselective PLE-catalyzed hydrolysis of meso-dimethyl tetrahydrophthalate on a 100 mole scale — protection of the enzyme by addition of bovine serum albumin.- Enantio- and diastereoselectivity of microsomal epoxide hydrolase: potential applications to the preparation of non-racemic epoxides and diols.- Efficient enzymic production of enantiomerically pure amino acids.- Biohydroxylation of non activated carbon atoms. A model for the hydroxylation site of the fungus beauveria sulfurescens.- “Sterols Bioconversions in systems with an organic phase”.- Second-generation biocatalysis.- Round-table discussions.- I. Nicotinamide recycling.- II. Enzymatic hydrolysis of nitriles, amides, urethanes and carbonates.- III. Enzymes in organic solvents. Enzymatic esterification.- IV. General discussion “Where do we go?”. Conclusions and suggestions.- — Chiral building blocks.- — Role of enzymes in protection and deprotection.- — Regioselective reactions using enzymes.- — New areas for enzyme applications.- — Artificial coenzymes, genetic — and proteinengineering.- — Requests from synthetic organic chemists.- — Final remarks.- List of contributors.

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