Enzymes – A Practical Introduction to Structure, Mechanism and Data Analysis 2e

Author:   RA Copeland
Publisher:   John Wiley & Sons Inc
Edition:   2nd Edition
ISBN:  

9780471359296


Pages:   416
Publication Date:   10 April 2000
Replaced By:   9781119793250
Format:   Hardback
Availability:   Awaiting stock   Availability explained


Our Price $435.60 Quantity:  
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Enzymes – A Practical Introduction to Structure, Mechanism and Data Analysis 2e


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Overview

Fully updated and expanded-a solid foundation for understanding experimental enzymology. This practical, up-to-date survey is designed for a broad spectrum of biological and chemical scientists who are beginning to delve into modern enzymology. Enzymes, Second Edition explains the structural complexities of proteins and enzymes and the mechanisms by which enzymes perform their catalytic functions. The book provides illustrative examples from the contemporary literature to guide the reader through concepts and data analysis procedures. Clear, well-written descriptions simplify the complex mathematical treatment of enzyme kinetic data, and numerous citations at the end of each chapter enable the reader to access the primary literature and more in-depth treatments of specific topics. This Second Edition of Enzymes: A Practical Introduction to Structure, Mechanism, and Data Analysis features refined and expanded coverage of many concepts, while retaining the introductory nature of the book. Important new features include: * A new chapter on protein-ligand binding equilibria * Expanded coverage of chemical mechanisms in enzyme catalysis and experimental measurements of enzyme activity * Updated and refined discussions of enzyme inhibitors and multiple substrate reactions * Coverage of current practical applications to the study of enzymology Supplemented with appendices providing contact information for suppliers of reagents and equipment for enzyme studies, as well as a survey of useful Internet sites and computer software for enzymatic data analysis, Enzymes, Second Edition is the ultimate practical guide for scientists and students in biochemical, pharmaceutical, biotechnical, medicinal, and agricultural/food-related research.

Full Product Details

Author:   RA Copeland
Publisher:   John Wiley & Sons Inc
Imprint:   John Wiley & Sons Inc
Edition:   2nd Edition
Dimensions:   Width: 16.70cm , Height: 2.70cm , Length: 24.10cm
Weight:   0.710kg
ISBN:  

9780471359296


ISBN 10:   0471359297
Pages:   416
Publication Date:   10 April 2000
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Replaced By:   9781119793250
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Awaiting stock   Availability explained

Table of Contents

A Brief History of Enzymology. Chemical Bonds and Reactions in Biochemistry. Structural Components of Enzymes. Protein-Ligand Binding Equilibria. Kinetics of Single-Substrate Enzyme Reactions. Chemical Mechanisms in Enzyme Catalysis. Experimental Measures of Enzyme Activity. Reversible Inhibitors. Tight Binding Inhibitors. Time-Dependent Inhibition. Enzyme Reactions with Multiple Substrates. Cooperativity in Enzyme Catalysis. Appendices. Index.

Reviews

...a welcome volume for any reader concerned with this important class of biological.... The book is interesting, informative, and very readable. (Choice, Vol. 38, No. 7, March 2001) ...an introductory textbook intended for senior undergraduate or graduate students...coverage includes chemical bonds and reactions, structural components of enzymes... (SciTech Book News, March 2001) ...to describe this text in one word, I would say that it is thorough...a good text for those interested in enzyme mechanisms and kinetics. (Journal of Medicinal Chemistry, Vol. 45, No. 235, 2002)


...a welcome volume for any reader concerned with this important class of biological... The book is interesting, informative, and very readable. (Choice, Vol. 38, No. 7, March 2001) ...an introductory textbook intended for senior undergraduate or graduate students...coverage includes chemical bonds and reactions, structural components of enzymes... (SciTech Book News, March 2001) ...to describe this text in one word, I would say that it is thorough...a good text for those interested in enzyme mechanisms and kinetics. (Journal of Medicinal Chemistry, Vol. 45, No. 235, 2002)


Author Information

ROBERT A. COPELAND, PhD, is Director of Chemical Enzymology at the DuPont Pharmaceuticals Company and Adjunct Professor of Biochemistry and Biophysics at the University of Pennsylvania School of Medicine.

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