Overview

Environmental Carcinogenesis, Volume 96 in the Advances in Pharmacology series, reports on work done with carcinogenic metals and the mechanisms of their carcinogenicity, including Arsenic and Chromate. Chapters in this release include Breast cancer carcinogenesis by organophosphate pesticides, Polyadenylation of Canonical histone H3.1 in Carcinogenesis, Epigenomic reprogramming in iAs-mediated carcinogenesis, MicroRNAs and epigenetic regulation in metal-induced angiogenesis and carcinogenesis, Environmental epigenetics and new mechanistic markers of chemical exposure, Arsenic carcinogenesis by inhibition of DNA repair, Genetic and environmental reprogramming of the sarcoma epigenome, Mechanism of chromate carcinogenesis by chromatin alterations, and more. Other chapters cover Arsenic carcinogenesis and microRNAs, Epigenetic mechanism of Cr(VI)-induced cell malignant transformation and tumorigenesis, The dark side of NRF2 in arsenic carcinogenesis, and Chemical mechanisms of DNA damage by carcinogenic chromium(VI).

Full Product Details

Author:   Max Costa (Chair and Professor, Department of Environmental Medicine, and Professor, Department of Biochemistry and Molecular Pharmacology, NYU School of Medicine, NY, USA)
Publisher:   Elsevier Science & Technology
Imprint:   Academic Press Inc
Weight:   0.760kg
ISBN:  

9780323997751

ISBN 10:   0323997759
Pages:   380
Publication Date:   24 February 2023
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Preface Max Costa 1. Mechanisms of chromate carcinogenesis by chromatin alterations Hesbon A. Zablon, Andrew VonHandorf and Alvaro Puga 2. Chemical mechanisms of DNA damage by carcinogenic chromium(VI) Casey Krawic and Anatoly Zhitkovich 3. The dark side of NRF2 in arsenic carcinogenesis Matthew Dodson, Jinjing Chen, Aryatara Shakya, Annadurai Anandhan and Donna D. Zhang 4. Breast carcinogenesis induced by organophosphorous pesticides Gloria M. Calaf 5. Tungsten toxicity and carcinogenesis Alicia M. Bolt 6. Arsenic and cancer: Evidence and mechanisms Rachel M. Speer, Xixi Zhou, Lindsay B. Volk, Ke Jian Liu and Laurie G. Hudson 7. miRNAs and arsenic-induced carcinogenesis Alexandra N. Nail, Ana P. Ferragut Cardoso, Lakyn K. Montero and J. Christopher States 8. Epigenetic and epitranscriptomic mechanisms of chromium carcinogenesis Zhishan Wang and Chengfeng Yang 9. Polyadenylation of canonical histone H3.1 in carcinogenesis Arul Veerappan, Aikaterini Stavrou and Max Costa 10. Genetic and environmental reprogramming of the sarcoma epigenome Anne Grand’Maison, Rachael Kohrn, Emmanuel Omole, Mahek Shah, Peter Fiorica, Jennie Sims and Joyce E. Ohm 11. Epigenomic reprogramming in iAs-mediated carcinogenesis Smitha George, Richard N. Cassidy, Wesley N. Saintilnord and Yvonne Fondufe-Mittendorf

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Author Information

Professor Max Costa's research interests include molecular mechanisms of metal carcinogenesis, cancer, pharmacology, epigenetics, and chromatin structure. Dr. Costa has published over 380 papers and has authored a book on Metal Carcinogenesis Testing. He serves on the Editorial Board as an Associate Editor for the Elsevier Journal, Toxicology and Applied Pharmacology.

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