Entry Inhibitors in HIV Therapy
Author:   Jacqueline D. Reeves ,  Cynthia A. Derdeyn
Publisher:   Birkhauser Verlag AG
Edition:   2007 ed.
ISBN:  

9783764377823


Pages:   206
Publication Date:   22 June 2007
Format:   Hardback
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

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Entry Inhibitors in HIV Therapy


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Overview

Entry Inhibitors in HIV Therapy details the current status of this relatively new and very dynamic class of inhibitors, appealing to both the clinician and basic research scientist. A unique overview of obstacles and accomplishments is presented. The book features chapters that explain the challenges of high sequence diversity in the viral envelope gene for the development and use of entry inhibitors, the clinical utility of virus phenotyping, the development of this class of inhibitors as microbicidal therapy, and the success story of enfuvirtide from the bench to FDA approval. Both basic research findings and results of clinical studies are covered and linked together by a diverse panel of experts in the field.

Full Product Details

Author:   Jacqueline D. Reeves ,  Cynthia A. Derdeyn
Publisher:   Birkhauser Verlag AG
Imprint:   Birkhauser Verlag AG
Edition:   2007 ed.
Weight:   0.569kg
ISBN:  

9783764377823


ISBN 10:   3764377828
Pages:   206
Publication Date:   22 June 2007
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

to entry inhibitors in the management of HIV infection.- The challenge of HIV sequence diversity in the envelope glycoprotein.- Attachment of human immunodeficiency virus to cells and its inhibition.- Inhibitors that target gp120-CD4 interactions.- Inhibitors that target gp120 interactions with coreceptor.- Inhibitors that target fusion.- HIV-1 entry inhibitors as microbicides.- Entry inhibition of HIV-1 subtype C isolates.- The utility of coreceptor typing in the clinic.- Future clinical prospects for entry inhibitors.- Enfuvirtide: from basic science to FDA approval.- Targets for drug development — past and present.

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