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OverviewThe gastrointestinal track provides one of the distinct systems where multiple malignancies, including adenocarcinoma of the pancreas, esophagus and colon are each associated with obesity. This unique association is covered in this volume of Energy Balance and Cancer from the epidemiologic, biologic and potential etiologic viewpoint. The focus on possible dietary contribution as well as the role of exercise in prevention and therapy is presented in both animal model and patient based studies. Special focus is provided also on the role of genetic mutations and inflammatory pathways as drivers of these obesity related gastrointestinal malignancies. Overall, this volume on Energy Balance and Gastrointestinal Malignancies should be valuable to Epidemiologists, Gastroenterologists and Oncologists, as well as to students and researchers from multiple disciplines interested in understanding and disrupting the association between obesity and cancer. Full Product DetailsAuthor: Sanford D. Markowitz , Nathan A. BergerPublisher: Springer-Verlag New York Inc. Imprint: Springer-Verlag New York Inc. Edition: 2012 ed. Volume: 4 Dimensions: Width: 15.50cm , Height: 1.30cm , Length: 23.50cm Weight: 0.308kg ISBN: 9781489989703ISBN 10: 1489989706 Pages: 184 Publication Date: 13 April 2014 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand ![]() We will order this item for you from a manufactured on demand supplier. Table of ContentsPreface.- Obesity and Gastrointestinal Cancers: Epidemiology.- Genetics of Colon Cancer Susceptibility.- Dietary Modulation of Colon Cancer: Effects on Intermediary Metabolism, Mucosal Cell Differentiation and Inflammation.- The ApcMin/+ Mouse Model to Study the Effects of Exercise on Gastrointestinal Malignancy.- Obesity and the Pathogenesis of Barrett’s Esophagus.- Obesity and Pancreatic Cancer.- Obesity, Insulin Resistance Pathway Factors and Colon Cancer.- Ras/Raf and their Influence in Glycolysis in Colon Cancer.- Energy Balance and Other Modifiable Host Factors on Colorectal Cancer Prognosis.- Cyclooxygenase-2 and Chronic Inflammation: Drivers of Colorectal Tumorigenesis.- Index.ReviewsFrom the reviews: In this book, leading investigators present a crossdisciplinary (basic, translational, and clinical science) view of the current state of the science on the links between gastrointestinal malignancy and energy balance. ... aimed at epidemiologists, gastroenterologists, and oncologists as well as students and researchers interested in understanding the connection between obesity and GI cancers ... . (Willem J. de Villiers, Doody's Review Service, July, 2012) From the reviews: In this book, leading investigators present a crossdisciplinary (basic, translational, and clinical science) view of the current state of the science on the links between gastrointestinal malignancy and energy balance. ... aimed at epidemiologists, gastroenterologists, and oncologists as well as students and researchers interested in understanding the connection between obesity and GI cancers ... . (Willem J. de Villiers, Doody's Review Service, July, 2012) From the reviews: In this book, leading investigators present a crossdisciplinary (basic, translational, and clinical science) view of the current state of the science on the links between gastrointestinal malignancy and energy balance. ... aimed at epidemiologists, gastroenterologists, and oncologists as well as students and researchers interested in understanding the connection between obesity and GI cancers ... . (Willem J. de Villiers, Doody's Review Service, July, 2012) Author InformationTab Content 6Author Website:Countries AvailableAll regions |