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OverviewFull Product DetailsAuthor: Christian Wahl-Schott , Martin BielPublisher: Springer International Publishing AG Imprint: Springer International Publishing AG Volume: 278 ISBN: 9783031315251ISBN 10: 3031315251 Pages: 304 Publication Date: 28 April 2024 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand We will order this item for you from a manufactured on demand supplier. Table of ContentsPart I: Physiological Functions of Endo-lysosomal Cation Channels.- NAADP-Mediated Ca2+ Signalling.- NAADP-Dependent TPC Current.- NAADP-Evoked Ca2+ Signaling: The DUOX2–HN1L/JPT2–Ryanodine Receptor 1 Axis.- TPC Functions in the Immune System.- Lysosomal Ion Channels and Lysosome– 1 Organelle Interactions.- TRPML1 and TFEB, an Intimate Affair.- Lysosomal Potassium Channels.- Part II Structure and Composition of TPC and TRPML Channels.- Structure and Function of Plant and Mammalian TPC Channels.- A Structural Overview of TRPML1 and the TRPML Family.- Endo-Lysosomal Two-Pore Channels and Their Protein Partners.- Part III: Tools and Methods to Characterize Endolysosomal Cation Channels.- Electrophysiological Techniques on the Study of Endolysosomal Ion Channels.- The Plant Vacuole as Heterologous System to Characterize the Functional Properties of TPC Channels.- Expanding the Toolbox: Novel Modulators of Endolysosomal Cation Channels.- Characterization of Endo-Lysosomal Cation Channels Using Calcium Imaging.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |