Overview

**Selected for Doody’s Core Titles® 2024 in Endocrinology/Metabolic Disease** Endocrine Hypertension: From Basic Science to Clinical Practice bridges the gap between scientists and practicing clinicians by providing a comprehensive overview on all forms of endocrine hypertension, covering epidemiological aspects, pathophysiology, clinical presentation, laboratory evaluation and practical management aspects of endocrine hypertension. This book is a great resource for endocrinologists, physicians, general practitioners and researchers who are eager to understand the complex facets of endocrine hypertension. Endocrine hypertension is a term used to describe a group of endocrine pathologies that cause an elevation of blood pressure, estimated to account for up to 10% of all hypertension cases. Although common, this clinical condition is often overlooked. Patients with this condition are at risk of late diagnosis, delayed treatment and detrimental health consequences.

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Reviews

The endocrine system is a complex creation, which maintains homeostasis in the body. Blood pressure, a physiological presence, ensures that the body a health entity. Hormones and blood pressure have a multifactorial relationship, characterized by quantum, entanglement at various levels. The causation, clinical features, comorbid conditions, complications and concerns of hypertension are linked closely with the endocrine system. In turn, knowledge of endocrinology provides a compass to understand and navigate the heterogeneity of hypertension. The book simplifies this structure and brings clarity to this complex discipline. From basic science to clinical practice , it systematically covers the adrenal and renal causes of hypertension, the contribution of the pituitary, thyroid and parathyroid glands, and the increasing role of metabolic disorders like obesity, insulin resistance and obstructive sleep apnea in the syndrome. The writers engage the reader in a journey through the wonderous world of physiology of blood pressure and pathogenesis of hypertension. Each page that I turn, each chapter that I read makes me feel like Alice in Wonderland, learning a new facet of health and disease. Endocrine hypertension is a book that I would commend to all health care professionals dealing with hypertension, both primary and secondary, and strongly recommend to students and clinicians of endocrinology and vascular medicine. -Dr. Sanjay Kalra I read with interest the textbook Endocrine Hypertension edited by J. M. Pappachan and C. J. Fernandez. The preparation of this book involves the participation of many leading scientists and clinicians that dedicated their studies to understanding the genetics and pathophysiology of the different hormonal systems involved in the regulation of blood pressure and the identification of the best clinical approaches for the management of the endocrine forms of hypertension. The present textbook should be therefore, of special interest not only for endocrinologists but for all categories of clinicians that are involved in the management of patients with hypertension, including general practitioners, internists, cardiologists, nephrologists and paediatricians. I predict that this book will be read with interest by many colleagues and should be used to support the specific learning of medical students and fellows. --Paolo Mulatero This comprehensive textbook on endocrine hypertension is a delight to read. The chapters are laid out very well with each topic covering the basic physiology and pathophysiology of endocrine hypertension. The flow charts, colourful graphical abstracts and tables make the reading and understanding of the complex clinical scenarios much easier. I am impressed with several of the authors who are internationally acclaimed and pioneers in the field whose contributions no doubt add tremendous value to the book. I no doubt feel this is a very useful textbook for any practicing consultant or trainee dealing with hypertension in general medicine and endocrinology. --Ganesan Arunagirinathan Professor Joseph M. Pappachan and Cornelius James Fernandez have put together an excellent textbook on Endocrine hypertension from basic science to clinical practice. The field of hypertension has been rapidly evolving, and more than a quarter of hypertension is due to endocrine aetiology. Hence this book has come at the correct time and provides an in-depth understanding of the various aetiologies of endocrine hypertension. The authors have handled the complicated topic of monogenic hypertension and endocrine hypertension in children in a much more practical way for understanding and implementation in day-to-day practice. Hence this is a holistic textbook that deals with the endocrine cause of hypertension from the womb to the tomb. I congratulate the editors for this excellent text and wish them good luck for future editions. This is a must-buy book for both the generalist and specialist for their daily practice and for the trainees in the area of general medicine, endocrinology, cardiology, renal medicine and general practice. --Mohammad Sadiq Jeeyavudeen This comprehensive textbook on endocrine hypertension is a delight to read. The chapters are laid out very well with each topic covering the basic physiology and pathophysiology of hypertension in endocrine disorders. The flow charts, colourful graphical abstracts and tables make the reading and understanding of the complex clinical scenarios much easier. I am impressed with several of the authors who are internationally acclaimed and pioneers in the field whose contributions no doubt add tremendous value to the book. The chapters on Cushing's and phaeochromocytoma are thorough and up to date linking closely with the current international guidelines. The chapter on endocrine hypertension in pregnancy is an excellent resource to the savvy endocrinologist with clear algorithms guiding us to deal with all possible scenarios. The dedicated chapter on imaging in endocrine disorders will no doubt prove to be a handy asset while choosing and organising the most appropriate investigation during workup. Finally, the chapter on endocrine hypertension in children, though very rare, will help in dealing with an unexpected teenager presenting with hypertension to the adult endocrinologist. I no doubt feel this is a very useful textbook for any practicing consultant or trainee dealing with hypertension in general medicine and endocrinology. 5.0 out of 5 stars - Brilliant resource on secondary hypertension --Dr. Ganesan Arunagirinathan, MD, FRCP, Senior Consultant Endocrinologist, University of Hospitals of Edinburgh, & Regional Advisor, Royal College of Physicians of Edinburgh, UK Professor Joseph M Pappachan and Dr. Cornelius James Fernandez have put together an excellent textbook on Endocrine hypertension from basic science to clinical practice. The field of hypertension has been rapidly evolving, and more than a quarter of hypertension is due to endocrine aetiology. Hence this book has come at the correct time and provides an in-depth understanding of the various aetiologies of endocrine hypertension. Each chapter starts with a graphical abstract summarising the content in a useful pictorial form. The pathophysiology section in the chapters is explained in an easy-to-understand format and yet addresses the complexity of the process involved in causing high blood pressure in various endocrine disorders. There are dedicated chapters explaining the concept of hypertension management due to pheochromocytoma, paragangliomas, Cushing syndrome, hyperaldosteronism, thyrotoxicosis, and growth hormone excess. The authors have handled the complicated topic of monogenic hypertension and endocrine hypertension in children in a much more practical way for understanding and implementation in day-to-day practice. Hence this is a holistic textbook that deals with the endocrine cause of hypertension from the womb to the tomb. I congratulate the editors for this excellent text and wish them good luck for future editions. This is a must-buy book for both the generalist and specialist for their daily practice and for the trainees in the area of general medicine, endocrinology, cardiology, renal medicine and general practice. 5.0 out of 5 stars - Must have this textbook ! --Dr. Sadiq Mohammed Jeeyavudeen MD, MRCP, Consultant Endocrinologist, Royal Infirmary of Edinburgh, University Hospitals of Edinburgh, UK

5.0 out of 5 stars - Brilliant resource on secondary hypertension; Dr. Ganesan Arunagirinathan, MD, FRCP, Senior Consultant Endocrinologist, University of Hospitals of Edinburgh, & Regional Advisor, Royal College of Physicians of Edinburgh, UK This comprehensive textbook on endocrine hypertension is a delight to read. The chapters are laid out very well with each topic covering the basic physiology and pathophysiology of hypertension in endocrine disorders. The flow charts, colourful graphical abstracts and tables make the reading and understanding of the complex clinical scenarios much easier. I am impressed with several of the authors who are internationally acclaimed and pioneers in the field whose contributions no doubt add tremendous value to the book. The chapters on Cushing's and phaeochromocytoma are thorough and up to date linking closely with the current international guidelines. The chapter on endocrine hypertension in pregnancy is an excellent resource to the savvy endocrinologist with clear algorithms guiding us to deal with all possible scenarios. The dedicated chapter on imaging in endocrine disorders will no doubt prove to be a handy asset while choosing and organising the most appropriate investigation during workup. Finally, the chapter on endocrine hypertension in children, though very rare, will help in dealing with an unexpected teenager presenting with hypertension to the adult endocrinologist. I no doubt feel this is a very useful textbook for any practicing consultant or trainee dealing with hypertension in general medicine and endocrinology. 5.0 out of 5 stars - Must have this textbook ! Dr. Sadiq Mohammed Jeeyavudeen MD, MRCP, Consultant Endocrinologist, Royal Infirmary of Edinburgh, University Hospitals of Edinburgh, UK. Professor Joseph M Pappachan and Dr. Cornelius James Fernandez have put together an excellent textbook on Endocrine hypertension from basic science to clinical practice. The field of hypertension has been rapidly evolving, and more than a quarter of hypertension is due to endocrine aetiology. Hence this book has come at the correct time and provides an in-depth understanding of the various aetiologies of endocrine hypertension. Each chapter starts with a graphical abstract summarising the content in a useful pictorial form. The pathophysiology section in the chapters is explained in an easy-to-understand format and yet addresses the complexity of the process involved in causing high blood pressure in various endocrine disorders. There are dedicated chapters explaining the concept of hypertension management due to pheochromocytoma, paragangliomas, Cushing syndrome, hyperaldosteronism, thyrotoxicosis, and growth hormone excess. The authors have handled the complicated topic of monogenic hypertension and endocrine hypertension in children in a much more practical way for understanding and implementation in day-to-day practice. Hence this is a holistic textbook that deals with the endocrine cause of hypertension from the womb to the tomb. I congratulate the editors for this excellent text and wish them good luck for future editions. This is a must-buy book for both the generalist and specialist for their daily practice and for the trainees in the area of general medicine, endocrinology, cardiology, renal medicine and general practice.

Author Information

Professor Pappachan M Joseph is a senior consultant Endocrinologist in the UK and honorary professor at the Manchester Metropolitan University. He is an associate editor to Frontiers in Clinical Diabetes & Healthcare, the World Journal of Diabetes, and TouchREVIEWS in Endocrinology. He is also in the editorial board member of the American Endocrine Society Journal – JCEM Case Reports, has fully edited multiple journal issues in the past, and is the lead editor to the Elsevier Textbook “Endocrine Hypertension: From Basic Science to Clinical Practice”. He has 135 scientific publications in his credit in peer reviewed journals and has several multinational research collaborations. His academic h-index is 35 with more than 4200 citations of his works to date. His research special interests include obesity, metabolic disorders including MAFLD, neuroendocrinology & parathyroid disorders. Dr. Cornelius James Fernandez MD, MRCP is a consultant endocrinologist at Pilgrim Hospital, United Lincolnshire Hospitals NHS Trust, Boston, UK. He graduated from Kottayam Medical College, and underwent internal medicine postgraduate training from Coimbatore Medical College (India) with further specialist training in Endocrinology in the U.K. He is a review editor to “Frontiers in Clinical Diabetes and Healthcare” and scientific peer reviewer to several other medical journals. He has authored 35 peer reviewed scientific papers to date in different medical journals and actively involves in clinical research programs in his hospital. His research special interests include endocrine hypertension, diabetic foot disease and diabesity.

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