Overview

This book describes methodology and applications for endocrine disrupter toxicity testing, an issue of considerable urgency, because of international regulatory authorities currently considering such testing schemes. The coverage examines major animal groups for sensitivity to endocrine disrupting chemicals (EDCs), identifying endpoints and procedures for testing guidelines. Three EDC screening methods (two using fish and one using amphibians) are examined in detail for their efficacy and applicability. Edited by, and with contributions from, a leading participant in regulatory efforts, the book outlines methods that combine sensitivity, efficiency, statistical power, acceptable cost, and minimum ethical concern.

Full Product Details

9781118355961

Table of Contents

Reviews

Author Information

PETER MATTHIESSEN, PhD, is an aquatic ecotoxicologist who works as an independent consultant. Specializing in the study of endocrine disrupters, he has conducted extensive research into how sewage effluents cause feminization in wild male fish as well as how tributyltin-based antifoulants cause masculinization in wild female mollusks. Professor Matthiessen is a member of the UK Advisory Committee on Pesticides and Co-chair of the OECD Validation Management Group for Ecotoxicity Tests. He has contributed to the development of standardized ecotoxicity assays with sensitivity for endocrine disrupters as well as written guidance for the interpretation of the resulting data.

Tab Content 6

Countries Available