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Author:   Vivek Gupta (Assistant Professor of Industrial Pharmacy and Pharmaceutics, St. John's University, NY, USA) ,  Mallesh Kurakula (Research Scientist Department of Biomedical Engineering, University of Memphis, TN, USA)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
ISBN:  

9780128226339

ISBN 10:   0128226331
Pages:   440
Publication Date:   01 March 2022
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Forthcoming
Availability:   Not yet available  
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Table of Contents

Part I - Fundamentals 1. Introduction to microfluidics - physics, and applications 2. Fluid Dynamics in microfluidics 3. Microfluidic-assisted organic synthesis 4. Introduction to microfabrication and applications in biomedical sciences Part II - Applications in Drug Discovery 5. Microfluidics in cell culture systems 6. Single-cell screening using microfluidic systems 7. Microfluidic Vascular Networks for Engineered Tissues 8. Microscale Models of Inflammatory Diseases 9. Lab-on-a-chip techniques for high throughput proteomics and drug discovery 10. Organ-on-chip systems for personalized medicine 11. Antibody discovery using microfluidic systems Part III - Applications in Drug Delivery 12. Microfabrication and Microfluidic Devices for Drug Delivery 13. Microfluidic mixing and devices for preparing nanoparticulate drug delivery systems 14. Droplet-based microfluidics for cell encapsulation and delivery 15. Lab-on-a-chip synthesis of microparticles for drug encapsulation and controlled release 16. Microfluidic technologies for local drug delivery 17. Applications of microfluidics for processing of biomaterials and nanomedicines 18. 3D printing using microfluidics Part IV - Applications in Diagnostics 19. Introduction, structuring, and application of electrowetting Theory (EWOD) Microsystems in diagnostics 20. Introduction, structuring, and application of liquid dielectrophoresis in diagnostics. 21. Digital microfluidics technologies for diagnostic devices 22. Microfluidic devices for stem cell analysis 23. Development of immunoassays for protein analysis on nanobioarray chips 24. Applications of disease/tumour 3D in vitro models Part V- Intellectual and Regulatory Perspective 25. Current and future impact of microfluidic technology 26. Challenges to scaling up, commercialization, intellectual property, and regulatory issues

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Dr. Vivek Gupta received his Ph.D. in pharmaceutical sciences from Texas Tech University Health Sciences Center, Amarillo, TX. He is currently an assistant professor of industrial pharmacy and pharmaceutics at St. John's University in New York City. He has more than 10 years of experience in formulation design for novel drug delivery systems for non-invasive delivery of therapeutics, pharmacokinetic and pharmacodynamic characterization of delivery systems for enhanced lung accumulation and bioavailability. Dr. Vivek Gupta's current research is focused on drug discovery and delivery of novel therapeutic agents for rare disorders of the cardiopulmonary system including pulmonary fibrosis, pulmonary hypertension, and mesothelioma, a rare form of lung cancer associated with asbestos exposure. Dr. Gupta has published 45 journal articles and book chapters in his research field. Dr. Mallesh Kurakula received his Ph.D. in Chemistry from King Abdul-Aziz University, Jeddah, KSA. He is currently a research scientist in the department of biomedical engineering at the University of Memphis, TN. He has a bachelor and postgraduation in pharmacy, having pharmaceutics as specialization. His research is focused on evaluating polymers/ phospholipids of different origins in formulating novel delivery systems intended for enhancing the bioavailability and efficacy of BCS II drugs via different routes. Delivery systems were developed using a cross-section of state-of-the-art technologies such as electrospinning, 3D printing, and high-pressure homogenizers. Currently, he is working on an NIH grant project. He has published his research and book chapters in reputed journals in the fields of pharmaceutics, biopolymers, nanotechnology and biomedical fields.

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