Full Product Details
Author: R. W. Hoffmann
Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition: 2009 ed.
Dimensions:
Width: 15.50cm
, Height: 1.20cm
, Length: 23.50cm
Weight: 0.454kg
ISBN: 9783540792192
ISBN 10: 3540792198
Pages: 227
Publication Date: 21 January 2009
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Paperback
Publisher's Status: Active
Availability: In Print
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Reviews
Aus den Rezensionen: ! Reinhard W Hoffmanns Buch gibt dem Studenten das Rustzeug fur erfolgreiche eigene Syntheseplanung in die Hand. Es ist kein Lehrbuch, das Grundlagen oder fortgeschrittenes Wissen der Organischen Chemie vermittelt, sondern hilft, dieses Wissen in der Syntheseplanung praktisch anzuwenden. Das gelingt dem Autor mit leichtverstandlicher Sprache und einfachen Graphiken, sowie ideal gewahlten Beispielen hervorragend. 'Elemente der Syntheseplanung' ! gibt dem fortgeschrittenen Studenten ! wertvolle Hinweise und neue Sichtweisen ... Fur fortgeschrittene Studenten und Leser, welche sich fur Syntheseplanung interessieren, ist die Lekture ! hochst empfehlenswert ! (http://www.organische-chemie.ch/buecher/besprechungen/3540792198.shtm)
From the reviews: From an undergraduate learning perspective the concept of synthesis planning or retrosynthesis can appear to be a daunting prospect. The idea of being asked to think backwards for many is a big leap, despite the vast majority already possessing a well-stocked chemical toolbox and being more than capable to explain a multitude of complex mechanistic transformations. In Elements of synthesis planning, a reworked translation of his original German text, Reinhard Hoffmann sets out to 'demystify' the art of synthetic planning, which is an essential and vital skill practised every day throughout the worldwide organic chemistry community. In 12 clear and logical chapters, Hoffmann takes the reader from the basic concepts of retrosynthesis (use of synthons, identifying key bond disconnections, unmasking symmetry elements etc) to dedicated chapters on the application of chiral building blocks, strategic planning of complex synthetic sequences and the synthesis of polycyclic ring systems. In the final chapter, all these concepts are brought together to elegantly compare several individual approaches to one of five representative natural products, highlighting the tactics and strategies employed. As such, this text would ideally complement an advanced undergraduate course on complex organic synthesis, which is beyond the level of most standard organic chemistry textbooks. It would also prove highly useful to postgraduates at the beginning of their research careers in synthesis to inspire creativity and maybe put their ideas into practice. Gordon Florence , Chemistry World, 2009, 6(8), p. 63 Aus den Rezensionen: ... Didaktisch geschickt fuhrt der Autor in die Prinzipien der retrosynthetischen Analyse ein; dabei ist die pragmatische Unterteilung in die Abschnitte 'Functional Group Oriented Bond-Sets', 'Skeleton Oriented Bond-Sets' und 'Building Block Oriented Bond-Sets' ausserst sinnvoll. ... Dann stellt das Buch eine Reihe von Synthons exemplarisch vor. ... Am Ende eines jeden Kapitels erhalt der Leser Aufgaben, fur die am Ende des Texts eine Losung steht. ... Es ist ein guter Einstieg fur all diejenigen, die einschlagige Erfahrungen in organischer Synthese besitzen ... (Dieter Hoppe, in: Nachrichten aus der Chemie, March/2010, Vol. 58, Issue 3, S. 379)
