Drugs from Nature: Targets, Assay Systems and Leads

Author:   Madhathilkovilakathu Haridas ,  Sabu Abdulhameed ,  Dileep Francis ,  Swaroop S Kumar
Publisher:   Springer Verlag, Singapore
Edition:   1st ed. 2024
ISBN:  

9789819991822


Pages:   568
Publication Date:   19 March 2024
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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Drugs from Nature: Targets, Assay Systems and Leads


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Author:   Madhathilkovilakathu Haridas ,  Sabu Abdulhameed ,  Dileep Francis ,  Swaroop S Kumar
Publisher:   Springer Verlag, Singapore
Imprint:   Springer Verlag, Singapore
Edition:   1st ed. 2024
ISBN:  

9789819991822


ISBN 10:   981999182
Pages:   568
Publication Date:   19 March 2024
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Chapter 1. History of therapeutic discovery from natural sources.- Chapter 2. The process of drug development from natural sources.- Chapter 3. Ayurveda-inspired reverse pharmacology in drug discovery.- Chapter 4. Contemporary approaches in drug target identification and validation.- Chapter 5. Assay systems for identification of drug leads: contemporary approaches.- Chapter 6. Computational biology in lead identification and drug development.- Chapter 7. Physiology of inflammatory responses to external and autoimmune agents of diseases.- Chapter 8. Non-steroidal anti-inflammatory drug leads from natural sources.- Chapter 9. Mechanisms of side effects of non-steroidal anti-inflammatory drugs.- Chapter 10. Therapeutic targets in cancer.- Chapter 11. Anti-neoplastic drug leads from plants and microbes.- Chapter 12. Anti-fungal, anti-bacterial, and anti-parasitic therapeutics from natural sources.- Chapter 13. Anti-viral therapeutics from plants and microbes.- Chapter 14. Cardiovascular therapeutics from natural sources.- Chapter 15.         Antidiabetics and antilipemics from nature.- Chapter 16. Therapeutic targets and drug leads for reproductive health.- Chapter 17. Drug leadsfor neuro-muscular disorders from natural sources.

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Madhathilkovilakath Haridas did his doctoral and postdoctoral studies in structural biology at AIIMS, New Delhi and Massey University, New Zealand, respectively. He was the first biologist to get trained in X-Ray crystallography of single crystals of proteins. He has solved several animal and plant protein crystal structures. He has one hundred and fifty-plus international publications and thirty-plus chapters in edited volumes. He has one international and two Indian patents. He has guided 26 students for their Ph.D. He is the founding honorary director of the Inter-University Centre for Bioscience, Kannur University. He has served in various academic bodies of all tiers of all universities in Kerala. Currently, he is a serving member of the Biotechnology Commission Kerala, Biodiversity Board Kerala, Research Council Amrita School of Ayurveda Kollam, Research Committee Arya Vaidya Pharmacy Coimbatore, and Research and Ethical Committee of MVR Cancer Centre & Research Institute, Kozhikode. Sabu Abdulhameed is a Professor at the Department of Biotechnology and Microbiology, Kannur University, India and is serving as Pro-Vice Chancellor of the University since January 2021. He received his Ph.D. from Cochin University of Science and Technology and served as a Scientist Fellow at CSIR-NIIST, Thiruvananthapuram. He did his postdoctoral research in microbial fermentation and biotransformation in the USA and France. His research interests are in microbial fermentation, therapeutic enzymes, and the biotransformation of bioactive molecules. He has contributed extensively to fermentation and biotransformation in medicated wines and has four patents to his credit. Dr. Sabu has published six books and nearly 100 research papers in international journals. He is a recipient of a postdoctoral fellowship from the Institute for Research and Development (IRD, France) and a Visiting Professorship from the Mexican Agency for International Cooperation and Development. He is also a member of many academic bodies and expert panels and serves on the editorial boards of numerous research journals. Dr. Dileep Francis, an Assistant Professor in the Department of Life Sciences at Kristu Jayanti College, Bengaluru, earned his Ph.D. In Life Sciences from Kannur University, India. Achieving an impressive all India rank of 60 in the CSIR-NET exam, he received research fellowships from the Council for Scientific and Industrial Research (CSIR) during his doctoral studies. Dr. Dileep's research accomplishments include identifying a vaccine candidate for Methicillin-resistant Staphylococcus aureus infections. Currently, his focus extends to interventions in diagnosing and treating infectious diseases, with recent explorations in material sciences for biomedical applications. With a robust publication record encompassing high-impact journals, book chapters, and popular science articles, Dr. Dileep also serves as the editor of the Kristu Jayanti Journal of Core and Applied Biology. He is a life member of the Kerala Academy of Sciences, a research advisory committee member at Kristu Jayanti College, and coordinates the Star College Scheme of the Department of Biotechnology, Government of India, at the college. Swaroop S Kumar is currently working as Assistant Professor, Department of Food Technology, Amal Jyothi College of Engineering, Kanjirappally. Kerala, India. He earned his Ph.D. in Biotechnology from Kannur University, Kerala, India. He has eight years of experience and published several papers in reputed national and international journals with an h-index of 9 and 225 citations. He also has one patent to his credit. He has been an invited speaker in many seminars and workshops and mentored several undergraduate student projects. He is also a member of various institutional academic bodies. He has also been an external evaluator for the young investigator program conducted by Kerala Development and Innovation and Strategic Council (K-DISC). He is a life member of the Biotech Research Society of India. His current research interest includes the production, purification, and characterization of therapeutic enzymes, protein engineering, and the characterization of bioactive molecules

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