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Author:   Dean S. Hsieh
Publisher:   Taylor & Francis Inc
Imprint:   Marcel Dekker Inc
Volume:   v. 62
Dimensions:   Width: 21.60cm , Height: 2.60cm , Length: 27.90cm
Weight:   0.816kg
ISBN:  

9780824790158

ISBN 10:   0824790154
Pages:   448
Publication Date:   17 September 1993
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Out of stock  

Table of Contents

Part 1 General introduction to drug permeation enhancement: understanding permeation enhancement technologies, Dean S. Hsieh; skin penetration enhancers - scientific perspectives, Vinod P. Shah; basic mechanisms in transepithelium transport enhancement, Wei-Chiang Shen and Yi-Jing Lin. Part 2 Drug permeation enhancement via the skin-chemical means: skin permeation enhancement reversibility, Margo B. Haberkamp; visualization of drug transport across human skin and the influence of penetration enhancers, H.E. Junginger et al; compatibility and synergy of permeation enhancers with solvents, excipients, and drugs, Shirley M. Ng; a general method for assessing skin permeation enhancement mechanisms and optimization, Charan R. Behl et al; permeation enhancement with ethanol - mechanism of action through skin, S. Yum et al; Liposomes as penetration promoters and localizers of topically applied drugs, Michael Mezei; barrier properties of skin-skin development and permeation, Tamie Kurihara-Bergstrom and William Good. Part 3 Drug permeation enhancement via the skin-physical means: Iontophoresis-fundamentals, Ooi Wong; transdermal delivery of proteins and peptides by Iontophoresis-development, challenges, and opportunities, Jue-Chen Liu and Ying Sun; In Vivo experience with electrically mediated transdermal drug delivery, B. Robert Meyer; In Vivo and In Vitro characteristics of electro-transermal drug delivery, Mary Martin and John Devane; transdermal drug delivery by phonophoresis-basics, mechanism, and techniques of application, Ying Sun and Jue-Chen Liu. Part 4 Drug permeation enhancement via the nasal route: permeability and metabolism as barriers to transmucosal delivery of peptides and proteins, Bruce J. Aungst; toxicological evaluation of intranasal peptide and protein drugs, Michael A. Dorato. Part 5 Drug permeation enhancement via the ocular route: permeation enhancement for ocular route of polypeptide administration, George C.Y. Chiou and Yu-Qun Zheng; mechanisms of ocular peptide absorption and its enhancement, Yongyut Rojanasakul.

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. . .easy to read and to understand. . ..a worthwhile addition to academic and industry libraries. ---Pharmaceutical Technology

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