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Full Product Details

Author:   Mukund S. Chorghade (Chorghade Enterprises)
Publisher:   John Wiley & Sons Inc
Imprint:   Wiley-Interscience
Dimensions:   Width: 18.80cm , Height: 2.90cm , Length: 26.20cm
Weight:   0.971kg
ISBN:  

9780471398486

ISBN 10:   0471398489
Pages:   476
Publication Date:   28 July 2006
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
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Table of Contents

Contributors. Preface. 1. From Patent to Prescription: Paving the Perilous Path to Profit (Richard J. Pariza). 2. Medicinal Chemistry in the New Millennium: A Glance into the Future (Paul W. Erhardt). ADMET-Related Synergies, 59 3. Contemporary Drug Discovery (Lester A. Mitscher and Apurba Dutta). 4. Combinatorial Chemistry in the Drug Discovery Process (Ian Hughes). 5. Parallel Solution-Phase Synthesis (Norton P. Peet and Hwa-Ok Kim). 6. Timing of Analog Research in Medicinal Chemistry (János Fischer and Anikó Gere). 7. Possible Alternatives to High-Throughput Screening (Camille G. Wermuth). 8. Proteomics and Drug Discovery (Susan Dana Jones and Peter G. Warren). Appendix: Public-Domain Software Tools and Databases. 9. Using Drug Metabolism Databases During Drug Design and Development (Paul W. Erhardt). 10. Discovery of the Antiulcer Drug Tagamet (C. Robin Ganellin). 11. Discovery of Potent Nonpeptide Vasopressin Receptor Antagonists (Bruce E. Maryanoff). 12. Discovery and Development of the Ultrashort-Acting Analgesic Remifentanil (Paul L. Feldman). 13. Discovery and Development of Nevirapine (Karl Grozinger, John Proudfoot, and Karl Hargrave). 14. Applications of Nuclear Imaging in Drug Discovery and Development (John W. Babich and William C. Eckelman). 15. Polymeric Sequestrants as Nonabsorbed Human Therapeutics (Pradeep K. Dhal, Chad C. Huval, and S. Randall Holmes-Farley). 16. Botanical Immunomodulators and Chemoprotectants in Cancer Therapy (Bhushan Patwardhan, Sham Diwanay, and Manish Gautam). Index.

Reviews

...provides a nice survey of most of the key topics facing discovery houses today. (Doody's Health Services) This reasonably priced book is well-written and produced. It has a useful 32-page index, and it may be considered for acquisition by individuals and libraries. (Journal of Medicinial Chemistry, October 5, 2006)

"""...provides a nice survey of most of the key topics facing discovery houses today."" (Doody's Health Services) ""This reasonably priced book is well-written and produced. It has a useful 32-page index, and it may be considered for acquisition by individuals and libraries."" (Journal of Medicinial Chemistry, October 5, 2006)"

Author Information

Mukund S. Chorghade, PHD, is President of Chorghade Enterprises, Inc., a firm based in Natick, Massachusetts that provides consultations to major pharmaceutical companieson collaborations with worldwide academic, government, and industrial laboratories; European technology-based companies; process reengineering; and project management of technology transfer.

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