Drug Development: Molecular Targets for GI Diseases
Author:   Timothy S. Gaginella ,  Antonio Guglietta
Publisher:   Humana Press Inc.
Edition:   2000 ed.
ISBN:  

9780896035898


Pages:   278
Publication Date:   01 September 1999
Format:   Hardback
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Our Price $303.60 Quantity:  
Add to Cart

Share |

Drug Development: Molecular Targets for GI Diseases


Add your own review!

Overview

Timothy Gaginella and Antonio Guglietta bring together hands-on experts to critically review the many promising new areas of gastrointestinal pharmacology at the molecular level. Key chapters discuss such major themes as cyclooxygenase-2 inhibitors, the complexities of nitric oxide pathways in the gut, and the influence of cytokines on inflammatory bowel disease, as well as new opportunities for pharmacotherapy, including peptide growth factors, achykinins - particularly substance P and neurokinins - cholecystokinin receptors, and serotonin. Also examined as possible sites for treating motility disorders and visceral pain are the opioid receptors residing in the gut, and the H3-receptor agonists for treating gut inflammation and pain. Drug Development: Molecular Targets for Gastrointestinal Disease provides a comprehensive review of today's molecular pharmacological approaches to the discovery and development of novel drugs for gastrointestinal and liver diseases.

Full Product Details

Author:   Timothy S. Gaginella ,  Antonio Guglietta
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   2000 ed.
Dimensions:   Width: 15.50cm , Height: 1.70cm , Length: 23.50cm
Weight:   1.290kg
ISBN:  

9780896035898


ISBN 10:   0896035891
Pages:   278
Publication Date:   01 September 1999
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

1 The Arachidonic Acid Pathway: New Molecules and Enzymes.- 2 Therapeutic Implications of the Nitric Oxide Pathway in Gastrointestinal Diseases.- 3 Cytokines: Opportunities for Therapeutic Intervention.- 4 Peptide Growth Factors in Gastrointestinal Disorder Therapeutics.- 5 Tachykinins: From Basic Concepts to Therapeutic Implications.- 6 CCKA Receptors in Gastrointestinal Disorders: New Therapeutic Implications.- 7 5-HT3/5-HT4 Receptors in Motility Disorders: New Therapeutic Agents.- 8 Opioid Receptors: Targets for New Gastrointestinal Drug Development.- 9 The Histamine H3 Receptor: Pharmacotherapy Targets in Gastrointestinal Disorders.

Reviews

The book focuses on specific molecules and the drugs that act on them, their receptors, metabolism or synthesis... a useful text for investigators of GI function and for pharmacologists interested in therapeutic compounds, their actions and targets. -Trends in Pharmaceutical Sciences


Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions
Latest Reading Guide

MRG2025CC

 

Shopping Cart
Your cart is empty
 Shopping cart
Mailing List

 

Sign up now