Drug Design: Cutting Edge Approaches
Author:   Darren R Flower (Aston University, UK)
Publisher:   Royal Society of Chemistry
Volume:   Volume 279
ISBN:  

9780854048168


Pages:   202
Publication Date:   07 October 2002
Format:   Hardback
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Our Price $219.94 Quantity:  
Add to Cart

Share |

Drug Design: Cutting Edge Approaches


Overview

Pharmaceutical research draws on increasingly complex techniques to solve the challenges of drug design. Bringing together a number of informatics techniques, this title looks at modelling and bioinformatic strategies; structural genomics and X-ray crystallography; virtual screening; lead optimisation; ADME profiling and vaccine design. A number of relevant case studies, focussing on techniques that have demonstrated their use, concentrate on G-protein coupled receptors as potential disease targets. The book should be useful to drug discovery scientists, including medicinal and combinatorial chemists, molecular modellers, bio- and cheminformaticians, pharmacologists, university and pharmaceutical company libraries.

Full Product Details

Author:   Darren R Flower (Aston University, UK)
Publisher:   Royal Society of Chemistry
Imprint:   Royal Society of Chemistry
Volume:   Volume 279
Dimensions:   Width: 15.60cm , Height: 1.30cm , Length: 23.40cm
Weight:   0.465kg
ISBN:  

9780854048168


ISBN 10:   0854048162
Pages:   202
Publication Date:   07 October 2002
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Introduction; High-Throughput X-Ray Crystallography for Drug Discovery; Bioinformatics in Drug Design: a GPCR case study; Virtual Screening of Virtual Libraries - an Efficient Strategy for Lead Generation; Virtual Techniques for Lead Optimisation; The Impact of Physical Organic Chemistry on the Control of Drug-like Properties; Mutagenesis and Modelling Highlight the Critical Nature of the TM2-loop-TM3 region of biogenic amine GPCRS; Computational Vaccine Design; Subject Index.

Reviews

... a book that can be understood by the lay person ... For anyone interested in reading about some individual facets of drug research, ...this book can be recommended. Angewandte Chemie, International Edition, Vol 42, No 22, June 2003, p 2446


""... a book that can be understood by the lay person ... For anyone interested in reading about some individual facets of drug research, ...this book can be recommended."" * Angewandte Chemie, International Edition, Vol 42, No 22, June 2003, p 2446 *


... a book that can be understood by the lay person ... For anyone interested in reading about some individual facets of drug research, ...this book can be recommended. * Angewandte Chemie, International Edition, Vol 42, No 22, June 2003, p 2446 *


Author Information

Tab Content 6

Author Website:  

Countries Available

All regions
Latest Reading Guide

NOV RG 20252

 

Shopping Cart
Your cart is empty
 Shopping cart
Mailing List

 

Sign up now