Drosophila Models for Human Diseases
Author:   Masamitsu Yamaguchi
Publisher:   Springer Verlag, Singapore
Edition:   Softcover reprint of the original 1st ed. 2018
Volume:   1076
ISBN:  

9789811344428


Pages:   308
Publication Date:   07 February 2019
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Drosophila Models for Human Diseases


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Overview

Most biological pathways, physical and neurological properties are highly conserved between humans and Drosophila and nearly 75% of human disease-causing genes have a functional homologue in Drosophila. This volume provides recent advances in Drosophila models for various human diseases, with each chapter providing a review of studies involving Drosophila models, as well as detailed protocols commonly used in laboratories. Starting with a review of Drosophila’s value as a highly tractable model organism for studying human diseases, subsequent chapters present Drosophila models for specific human diseases. The book provides a useful resource for all scientists who are starting to use the Drosophila model in their studies, and for researchers working in the pharmaceutical industry and using new screening models to develop new medicines for various diseases. 

Full Product Details

Author:   Masamitsu Yamaguchi
Publisher:   Springer Verlag, Singapore
Imprint:   Springer Verlag, Singapore
Edition:   Softcover reprint of the original 1st ed. 2018
Volume:   1076
Weight:   0.829kg
ISBN:  

9789811344428


ISBN 10:   9811344426
Pages:   308
Publication Date:   07 February 2019
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Ch1 Drosophila as a model organism.-Ch2 Adult intestine aging model.-Ch3 Alzheimer’s disease model.-Ch 4 Parkinson’s disease model.-Ch 5 Repeat expansion disease model.-Ch 6 Amyotrophic lateral sclerosis model.-Ch7 Charcot-Marie-Tooth disease model.-Ch8 Role of long non-coding RNA in neurological diseases.-Ch9 Muscular dystrophy model.-Ch10 Cancer model.-Ch11 Leukemia model.-Ch12 Diseases of replication /repair genes.-Ch13 Drosophila models for studying UPR in insulin-like peptide producing cells and onset of type I diabetes.-Ch14 Metabolomics study on Drosophila models.-Ch15 Humanized flies for functional analysis of the human genome and cross-species comparison.-Ch16 Designs for Flies

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Author Information

Masamitsu Yamaguchi received his PhD from Osaka University and is currently a Professor of Applied Biology, Kyoto Institute of Technology. He is a former director of the Advanced Insect Research Promotion Center at Kyoto Institute of Technology. 

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