Overview

DNA sequencing techniques have evolved rapidly in recent years ' largely resulting from the Human Genome Project ' but scientists still encounter challenges in sequencing genomes. DNA Sequencing: Optimizing the Process and Analysis was written to help scientists sequence difficult templates. It is also a practical guide to faster and more efficient routine DNA sequencing. This in-depth volume covers important topics in the field, including biochemical and technological advances stemming from the Human Genome Project, proven and newly emerging methods of preparing DNA templates, the effects of widely used laboratory reagents on DNA sequencing, Laboratory Information Management Systems (LIMS), setting up of a GLP/GMP DNA sequencing lab, and the future of DNA sequencing.

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Dr. Jan Kieleczawa earned his masters and Ph.D. degrees from the University of Wroclaw (Poland) and his M.B.A. from Oakdale College. Currently, he heads the DNA Sequencing Group at Wyeth Research in Cambridge, MA. His research interest involve developing methods of sequencing numerous types of difficult DNA templates.

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